首页> 外文期刊>Virology >PREVALENCE AND GEOGRAPHIC GENETIC VARIATION OF HANTAVIRUSES OF NEW WORLD HARVEST MICE (REITHRODONTOMYS) - IDENTIFICATION OF A DIVERGENT GENOTYPE FROM A COSTA RICAN REITHRODONTOMYS MEXICANUS
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PREVALENCE AND GEOGRAPHIC GENETIC VARIATION OF HANTAVIRUSES OF NEW WORLD HARVEST MICE (REITHRODONTOMYS) - IDENTIFICATION OF A DIVERGENT GENOTYPE FROM A COSTA RICAN REITHRODONTOMYS MEXICANUS

机译:新世界捕食小鼠(倒齿牙菌)的花丝病的流行和地理遗传变异-从哥斯达黎加哥斯达黎加倒齿牙菌(REITHRODONTOMYS MEXICANUS)的不同基因型的鉴定

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We recently described a novel hantavirus (HMV-1) of the western harvest mouse Reithrodontomys megalotis. Screening of 181 additional specimens of Reithrodontomys from the United States and Mexico, including samples of R, mexicanus, R. sumichrasti, and R, gracilis of Costa Rica, for antibodies to hantavirus nucleocapsid protein revealed a widespread enzootic of hantavirus infection. Genetic analyses of 7 S genomes of Reithrodontomys-associated hantaviruses demonstrated that the enzootic of HMV-1 extends from central Mexico into the southwestern United States. A presumed deer mouse hantavirus was found in an R. megalotis animal in Mexico. A highly divergent HMV-1-like virus, tentatively called HMV-2, was identified in a Costa Rican R. mexicanus. These data suggest a longstanding radiation of hantaviruses among New World harvest mice. We identify possible opportunities for genetic exchange among hantaviruses of related rodent hosts. (C) 1995 Academic Press, Inc.
机译:我们最近描述了西部收获小鼠巨型齿状牙髓切开术的新型汉坦病毒(HMV-1)。筛选了来自美国和墨西哥的181例牙髓切开术标本,包括哥斯达黎加的R. mexicanus,R。sumichrasti和R. gracilis的样本,以检测汉坦病毒核衣壳蛋白的抗体,发现汉坦病毒感染已广泛存在。对与轮齿切开术相关的汉坦病毒的7个S基因组进行的遗传分析表明,HMV-1的生虫从墨西哥中部延伸到美国西南部。在墨西哥的巨型罗非鱼中发现了推测的鹿小鼠汉坦病毒。在哥斯达黎加墨西哥R. mexicanus中发现了一种高度不同的HMV-1类病毒,暂时称为HMV-2。这些数据表明,汉坦病毒在新大陆收获小鼠中长期辐射。我们确定相关啮齿动物宿主的汉坦病毒之间遗传交换的可能机会。 (C)1995 Academic Press,Inc.

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