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首页> 外文期刊>Weed Science: Journal of the Weed Science Society of America >The herbicide saflufenacil (KixorTM) is a new inhibitor of protoporphyrinogen IX oxidase activity.
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The herbicide saflufenacil (KixorTM) is a new inhibitor of protoporphyrinogen IX oxidase activity.

机译：除草剂苯丁草胺（Kixor TM ）是原卟啉原IX氧化酶活性的一种新型抑制剂。

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Saflufenacil (KixorTM) is a new herbicide of the pyrimidinedione chemical class for preplant burndown and selective preemergence dicot weed control in multiple crops, including corn. In this study, the mode of action of saflufenacil was investigated. For initial characterization, a series of biotests was used in a physionomics approach for comprehensive physiological profiling of saflufenacil effects. With the use of treated duckweed plants, metabolite profiling was performed based on quantification of metabolite changes, relative to untreated controls. Physiological and metabolite profiling suggested a mode of action similar to inhibitors of protoporphyrinogen IX oxidase (PPO) in tetrapyrrole biosynthetic pathway. Saflufenacil inhibited PPO enzyme activity in vitro with 50% inhibition of 0.4 nM for the enzymes isolated from black nightshade, velvetleaf, and corn. PPO inhibition by saflufenacil caused accumulations of protoporphyrin IX (Proto) and hydrogen peroxide (H2O2) in leaf tissue of black nightshade and velvetleaf. In corn, only slight increases in Proto and H2O2 were found, which reflects in planta tolerance of this crop. The results show that saflufenacil is a new PPO-inhibiting, peroxidizing herbicide.
机译：Saflufenacil（Kixor TM ）是嘧啶二酮化学类别的一种新型除草剂，可在包括玉米在内的多种农作物中进行种植前燃尽和选择性的出苗双子叶植物杂草控制。在这项研究中，研究了氟苯乙胺的作用方式。为了进行初步表征，在生理学方法中使用了一系列生物测试来对沙丁草胺作用进行全面的生理分析。使用处理的浮萍植物，相对于未处理的对照，基于代谢物变化的定量进行了代谢物谱分析。生理和代谢产物分析表明，其作用机理与四吡咯生物合成途径中的原卟啉原IX氧化酶（PPO）抑制剂相似。沙氟氰胺在体外抑制PPO酶的活性，对于从黑茄属植物，丝绒和玉米中分离的酶，其0.4％的抑制率为50％。氟苯嘧啶对PPO的抑制作用导致黑色茄科植物和绒毛的叶片组织中原卟啉IX（Proto）和过氧化氢（H 2 O 2 ）积累。在玉米中，仅发现Proto和H 2 O 2 略有增加，这反映了该作物的植物耐性。结果表明，氟苯那西酯是一种新的抑制PPO的过氧化除草剂。

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