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Immunohistochemical and in situ hybridized histochemical studies of SP and SPmRNA in early human placenta

机译:早期人类胎盘中SP和SPmRNA的免疫组织化学和原位杂交组织化学研究

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摘要

Previous studies have demonstrated that the human placental villi contain neuropeptide Y (NPY), somatostatin (SS) and β-endorphin (β-EP) neuropeptidies, suggesting that the neuropeptides might play an important role in development of the placenta and feta. SP is a neuropeptide and was discovered earliest. It functions importantly in regulating blood circulation. But up to now, SP existing in human placenta has never been reported. In this experiment, we used immunohistochemical method and in situ hybridization at gene transcriptive and translated level to study whether the human placenta can produce SP and what kind of cells in the placenta can produce SP, and to supply morphological evidence for studying functional significance of the SP in placenta and feta development.
机译:先前的研究表明,人胎盘绒毛中含有神经肽Y(NPY),生长抑素(SS)和β-内啡肽(β-EP)神经肽,表明神经肽可能在胎盘和胎儿的发育中起重要作用。 SP是一种神经肽,最早被发现。它在调节血液循环中起重要作用。但是到目前为止,尚未有人报道存在于人胎盘中的SP。在本实验中,我们使用免疫组织化学方法和基因转录和翻译水平的原位杂交研究人类胎盘是否可以产生SP,以及胎盘中什么样的细胞可以产生SP,并提供形态学证据来研究胎盘的功能意义。 SP在胎盘和胎儿发育中。

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