The synthesis, bioactivity and paramagnetic resonance of angiotensin I and its spin labelled derivative

WANG Rui; LI Xiaoxu; HUXiaoyu; Nl Jingman; LI Changling; LU Jingfen

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The synthesis, bioactivity and paramagnetic resonance of angiotensin I and its spin labelled derivative

机译：血管紧张素I及其自旋标记衍生物的合成，生物活性和顺磁共振

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ANGIOTENSIN II (Ang II ) is an important constituent in renin-angiotension system (RAS). The amino acid sequence of Ang II is DRVYIHPF. Ang II plays an important role both in maintenance of normal blood pressure and in occurrence of hypertension. AngII binding receptor can induce many kinds of physiological effects. Spin labeling is an effective method that greatly deepened the knowledge in structure, movement and interaction of biological molecules. For example, it has been used in studying interaction of antigen and antibody successfully. Some stable free radical compounds are not only informational but also functional.

机译：血管紧张素II（Ang II）是肾素-血管紧张素系统（RAS）的重要组成部分。 Ang II的氨基酸序列是DRVYIHPF。 Ang II在维持正常血压和发生高血压中均起重要作用。 AngII结合受体可以诱导多种生理作用。旋转标记是一种有效的方法，可以大大加深生物分子的结构，运动和相互作用的知识。例如，它已成功地用于研究抗原和抗体的相互作用。一些稳定的自由基化合物不仅具有参考意义，而且具有功能性。

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《Chinese science bulletin》 |1997年第21期|共3页
作者
WANG Rui; LI Xiaoxu; HUXiaoyu; Nl Jingman; LI Changling; LU Jingfen;
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正文语种 eng
中图分类自然科学现状及发展;
关键词
spin labelled angiotensin II; solid phase peptide synthesis; bioactivity; electron spin resonance;

机译：自旋标记血管紧张素Ⅱ;固相肽合成;生物活性;电子自旋共振;

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1. The synthesis, bioactivity and paramagnetic resonance of angiotensin I and its spin labelled derivative [J] . WANG Rui, LI Xiaoxu, HUXiaoyu, Chinese science bulletin . 1997,第21期

机译：血管紧张素I及其自旋标记衍生物的合成，生物活性和顺磁共振
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机译：顺磁弛豫试剂对15N自旋弛豫的影响及Gd（dpm）3作为氮-15核磁共振自旋标记的应用

The synthesis, bioactivity and paramagnetic resonance of angiotensin I and its spin labelled derivative

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