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首页> 外文期刊>World Journal of Surgery: Official Journal of the Societe Internationale de Chirurgie, Collegium Internationale Chirurgiae Digestivae, and of the International Association of Endocrine Surgeons >Gastric emptying function in patients 5 years after pylorus-preserving distal gastrectomy with or without preserving pyloric and hepatic branches of the vagal nerve for early gastric cancer.
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Gastric emptying function in patients 5 years after pylorus-preserving distal gastrectomy with or without preserving pyloric and hepatic branches of the vagal nerve for early gastric cancer.

机译:保留幽门远端胃切除术后5年,伴或不伴迷走神经幽门和肝分支保留胃癌早期患者的胃排空功能。

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摘要

BACKGROUND: To clarify the significance of preserving pyloric and hepatic branches of the vagal nerve (PHV) after pylorus preserving distal gastrectomy (PPG) for early gastric cancer, the author investigated the postgastrectomy syndrome and gastric emptying function at 5 years in PPG patients with or without preserving the PHV. METHODS: A total of 18 subjects (mucosal cancers) who underwent PPG with D1 lymph node dissection and preserving the PHV; they comprised group A-12 men and 6 women aged 38-68 years (mean 58.9 years). They were interviewed to inquire about gastrointestinal symptom (appetite, weight loss, gastric fullness, reflux esophagitis, early dumping syndrome) and then were compared with 24 PPG patients (submucosal cancers) with D2 lymph node dissection without preserving the PHV (group B-16 men and 8 women aged 33 to 69 years, mean 60.1 years). Esophagogastric endoscopy, abdominal ultrasonography, and gastric emptying function tests (GET) were undertaken, the latter by both radioisotope (solid diet) and acetaminophen (liquid diet) methods. RESULTS: There were no differences in the postoperative gastrointestinal symptoms, endoscopic reflux esophagitis, or endoscopic mucosal edema and redness (gastropathy) between groups A and B. However, more cholecystolithiasis (gallbladder stones) was found in group A than in group B, with the difference being significant (P < 0.0391). The GET for solid diet and liquid diet were the almost same among groups A and B. CONCLUSIONS: There were no significant differences in the postoperative QOL and GET between PPG patients with preserving PHV and those without preserving PHV. Cholecystolithiasis was only found in patients without preserving PHV.
机译:背景:为了阐明保留幽门远端胃切除术(PPG)对早期胃癌术后保留迷走神经的幽门和肝分支(PHV)的重要性,作者调查了患有或患有PPG的PPG患者5年后的胃切除术后综合征和胃排空功能不保留PHV。方法:共有18名接受PPG D1淋巴结清扫术并保存PHV的受试者(粘膜癌)。他们包括年龄在38-68岁(平均58.9岁)的A-12组男性和6名女性。他们接受了询问以了解胃肠道症状(食欲,体重减轻,胃饱满,反流性食管炎,早期倾倒综合征),然后与24例DPG淋巴结清扫而未保留PHV的PPG患者(粘膜下癌)进行了比较(B-16组)男性和8位女性,年龄分别为33至69岁(平均60.1岁)。进行了食管胃镜,腹部超声检查和胃排空功能测试(GET),后者通过放射性同位素(固体饮食)和对乙酰氨基酚(液体饮食)方法进行。结果:A组和B组的术后胃肠道症状,内窥镜反流性食管炎或内窥镜黏膜水肿和发红(胃病)无差异。但是,A组的胆囊结石症(胆囊结石)多于B组。差异显着(P <0.0391)。结论:A组和B组的固体饮食和流质饮食的GET几乎相同。结论:保留PHV和未保留PHV的PPG患者的术后QOL和GET差异无统计学意义。胆囊结石仅在不保留PHV的患者中发现。

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