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首页> 外文期刊>World journal of urology >Urological surgery in patients with hemorrhagic bleeding disorders Hemophilia A, Hemophilia B, von Willebrand disease: A retrospective study with matched pairs analysis
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Urological surgery in patients with hemorrhagic bleeding disorders Hemophilia A, Hemophilia B, von Willebrand disease: A retrospective study with matched pairs analysis

机译：出血性出血患者的泌尿外科手术：A型血友病，B型血友病，von Willebrand病：配对分析的回顾性研究

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Purpose: To determine retrospectively the perioperative management and outcome of transurethral prostate/bladder surgery (TURP, TURB) and transrectal prostate biopsy in hemophiliacs. Methods: Thirty-seven hemophilic patients underwent TURP (12 patients), TURB (13 patients), or transrectal prostate biopsy (12 patients) with proactive hemostaseological management (i.e., factor supply, close meshed hemostaseological analysis). Thirty-seven non-hemophiliac patients served as matched pairs who matched for age, gender, accompanying diseases, and the type of surgical procedure. The resulting pairs were analyzed for duration of surgery, hospital stay, and complications. Results: Average TURP length in hemophiliacs was 77.92 min, in the matched pairs group TURP 67.08 min (p = 0.487). Mean TURB length in hemophiliacs was 43.46 min versus 35.38 min in controls (p = 0.678). More important, the length of hospital stay was significant longer in the hemophiliacs undergoing TURP compared to non-hemophiliac control group (12.08 days vs. 5.83 days; p < 0.001). In TURB patients, similar results were found (11.15 days hemophiliacs vs. 6.15 controls; p = 0.018). Regarding complications (bleeding, hemorrhage, readmission), no significant difference between the groups was obtained. Conclusion: Urological interventions in hemophiliac patients with factor supply have the same risk for postoperative complications as in non-hemophiliacs. The only significant difference between hemophiliacs and non-hemophiliacs was the length of hospital stay.
机译：目的：回顾性确定血友病患者经尿道前列腺/膀胱手术（TURP，TURB）和经直肠前列腺活检的围手术期处理和结果。方法：对37例血友病患者进行TURP（12例），TURB（13例）或经直肠前列腺穿刺活检（12例）并进行了积极的血液酶学处理（即因子供应，紧密网状血液酶学分析）。三十七名非血友病患者按年龄，性别，伴随疾病和外科手术类型配对。分析所得的手术对的持续时间，住院时间和并发症。结果：血友病患者的平均TURP长度为77.92分钟，配对组TURP为67.08分钟（p = 0.487）。血友病患者的平均TURB长度为43.46分钟，而对照组为35.38分钟（p = 0.678）。更重要的是，与非血友病对照组相比，接受TURP的血友病患者的住院时间明显更长（12.08天vs. 5.83天; p <0.001）。在TURB患者中，发现了相似的结果（血友病患者为11.15天，对照组为6.15; p = 0.018）。关于并发症（出血，出血，再入院），两组之间无显着差异。结论：有血红蛋白供应的血友病患者的泌尿外科干预与非血友病患者发生术后并发症的风险相同。血友病患者和非血友病患者之间唯一的显着差异是住院时间。

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