...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>World's Poultry Science journal >Thermostable vaccines for Newcastle disease: a review
【24h】

Thermostable vaccines for Newcastle disease: a review

机译：用于新城疫的热稳定疫苗：综述

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Newcastle Disease (ND) is regarded as one of the major diseases of poultry because of the devastating losses that the virulent form of the ND virus can impose on both commercial and domestic chickens. However, the disease can be controlled through the administration of effective vaccines. Almost all the commercially available ND vaccines require refrigeration and begin to deteriorate rapidly after 1-2 hours if left at room temperature (around 25 degrees C). Subsequently, because maintaining an adequate supply of refrigerated facilities may be a difficult task in many countries with unreliable electrical supplies, the development and large scale production of an effective thermostable ND vaccine seems imperative to support the poultry industry. Such vaccines should be resilient to damage associated with either very cold or hot environments so there are no concerns about the viability of the vaccine in response to temperatures fluctuations that can occur in extreme environments when the difference in temperature during cold and warm seasons can vary greatly. In the following review paper, the development of such a vaccine is discussed, including molecular characterisation, organ tropism of vaccine strains, production, as well as administration methods and their efficacy. It addition, the potential payback has been calculated alongside opportunities provided by removing vaccines from cold chain storage.
机译：新城疫（ND）被认为是家禽的主要疾病之一，这是因为有毒力的ND病毒可对商业和家用鸡造成严重破坏。然而，可以通过施用有效疫苗来控制该疾病。几乎所有市售的ND疫苗都需要冷藏，并且如果置于室温（约25摄氏度），则在1-2小时后会开始迅速恶化。随后，由于在许多电力供应不可靠的国家中，保持足够的冷藏设施供应可能是一项艰巨的任务，因此开发和大规模生产有效的热稳定ND疫苗似乎对支持家禽业至关重要。这样的疫苗应能抵抗非常冷或炎热环境造成的损害，因此，当寒冷和温暖季节的温度差异变化很大时，在极端环境下可能发生的温度波动，疫苗的生存能力就不会受到关注。 。在下面的综述文件中，讨论了这种疫苗的开发，包括分子表征，疫苗株的器官嗜性，生产以及给药方法及其功效。此外，还计算了潜在的回报以及从冷链存储中移除疫苗所带来的机会。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号