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The yeast Ty virus-like particles [Review]

机译:酵母Ty病毒样颗粒[综述]

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摘要

Virus-like particle (VLP) assembly is a crucial step of the life cycle of retrotransposons. The S. cerevisiae Ty elements represent an interesting model for the analysis of these South Parks Road, Oxford particles and thus have been studied extensively. Our current knowledge of the organisation and assembly of Ty1 and Ty3 VLPs is reviewed here. This includes the mechanism of assembly, the role of the Tya core protein during VLP formation and the RNA packaging process, The physical properties of Ty1 VLPs are also described and the latest three-dimensional Ty1 VLP reconstructions are shown. In addition, the relevance of these studies is discussed in the contest of retro-element biology. Copyright (C) 2000 John Wiley & Sons, Ltd.
机译:病毒样颗粒(VLP)组装是逆转座子生命周期的关键步骤。酿酒酵母Ty元素代表了分析这些南公园路牛津颗粒的有趣模型,因此已被广泛研究。这里介绍了我们目前对Ty1和Ty3 VLP的组织和组装的了解。这包括组装机制,Tya核心蛋白在VLP形成过程中的作用以及RNA包装过程。还描述了Ty1 VLP的物理特性,并显示了最新的三维Ty1 VLP重建。此外,这些研究的相关性在后元素生物学竞赛中进行了讨论。版权所有(C)2000 John Wiley&Sons,Ltd.

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