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首页> 外文期刊>Head and neck: Journal for the sciences and specialities of the head and neck >Central adenoid cystic carcinoma of the mandible with odontogenic features: Report of a case.
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Central adenoid cystic carcinoma of the mandible with odontogenic features: Report of a case.

机译：下颌骨中央性腺样囊性癌，具有牙源性特征：病例报告。

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摘要

BACKGROUND: Primary intraosseous salivary-type adenocarcinomas are rare neoplasms of uncertain histogenesis. The prevailing theories suggest origin from heterotopic salivary glands, odontogenic rests, or cystic epithelium. METHODS: A case of central adenoid cystic carcinoma is reported in a 53-year-old woman who presented with a painless swelling in the anterior segment of her lower jaw. Radiographic examination confirmed the presence of an expansile, radiolucent lesion within the mandible with a multilocular appearance. On light microscopy analysis, areas showing cribriform and tubular growth patterns; admixed cysts, some of which were characterized by the presence of localized plaque-like thickenings of their epithelial linings; and the formation of aberrant dental hard tissue were observed. RESULTS: The radiographic and histomorphologic findings highlight the potential misdiagnosis of this rare tumor. The findings also draw attention to an embryologic histogenetic concept for some central salivary neoplasms. CONCLUSION: The divergent salivary and odontogenic differentiation evident in this tumor signifies the pluripotential nature of derivatives of oral ectoderm.
机译：背景：原发性骨内唾液型腺癌是罕见的组织发生不确定的肿瘤。流行的理论表明起源于异位唾液腺，牙源性休憩或囊性上皮细胞。方法：据报道，一名53岁的女性患有中央腺样囊性癌，其下颌前段无痛性肿胀。影像学检查证实在下颌骨中存在多发性外观的可扩张的，射线可透的病变。在光学显微镜分析中，区域显示出网状和管状的生长模式。混合性囊肿，其中一些特征在于其上皮内层存在局部斑块样增厚;观察到异常牙齿硬组织的形成。结果：影像学和组织形态学检查结果突显了这种罕见肿瘤的潜在误诊。这些发现还引起人们对某些唾液中央肿瘤的胚胎组织学概念的关注。结论：该肿瘤中唾液和牙源性分化的差异表明口腔外胚层衍生物的多能性。

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