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Some methodological issues with the analysis of preference-based EQ-5D index score

机译:基于偏好的EQ-5D指数得分分析的一些方法论问题

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摘要

The EQ-5D index is widely used to assess the preference-based health status. In this paper, we examine the analytical issues of regression models for the US preference-based EQ-5D index score. We propose a two-part approach to model the special features of the EQ-5D index. The first part is a logistic model for the probability of reaching the maximum score 1.0. The second part is a model for the rest of the scores that are less than 1.0, which can be a least squares regression with robust standard errors for the conditional mean, or a quantile regression for conditional quantiles such as the median. We show that the two-part model has some desirable features that are not available in the previously published regression methods for the EQ-5D index. We illustrate the proposed approach with data from the Medical Expenditure Panel Survey. The proposed method may be used for other utility or health related quality of life scores of similar features.
机译:EQ-5D指数被广泛用于评估基于偏好的健康状况。在本文中,我们研究了基于美国偏好的EQ-5D指数得分的回归模型的分析问题。我们提出了一种分为两部分的方法来对EQ-5D索引的特殊功能进行建模。第一部分是达到最大分数1.0的概率的逻辑模型。第二部分是其余分数小于1.0的模型,可以是最小二乘回归和条件均值的稳健标准误差,也可以是条件分位数(例如中位数)的分位数回归。我们表明,由两部分组成的模型具有一些理想的功能,这些功能在以前发布的EQ-5D索引回归方法中不可用。我们用医疗支出小组调查的数据说明了建议的方法。所提出的方法可以用于相似特征的其他与生活或健康相关的生活质量得分。

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