Diversity of Helicobacter pylori cagA and vacA Genes in Costa Rica: Its Relationship with Atrophic Gastritis and Gastric Cancer

Sergio A. Con; Hiroaki Takeuchi; Ana L. Valerin; Reinaldo Con-Wong; Gil R. Con-Chin; Vicky G. Con-Chin; Mitsuaki Nishioka; Fernando Mena; Fernando Brenes; Nobufumi Yasuda

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Diversity of Helicobacter pylori cagA and vacA Genes in Costa Rica: Its Relationship with Atrophic Gastritis and Gastric Cancer

机译：哥斯达黎加的幽门螺杆菌cagA和vacA基因多样性：与萎缩性胃炎和胃癌的关系

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Background: Associations between Helicobacter pylori gene diversity and gastric cancer have not been reported on in Costa Rica, despite its being one of the countries with the highest gastric cancer incidence and mortality rates in the world. The aim of this study was to determine the prevalence of H. pylori cagA and vacA genes and investigate whether it could be correlated with atrophic gastritis (AG) and gastric cancer (GC) in Costa Rica.

机译：背景：尽管哥斯达黎加是世界上胃癌发病率和死亡率最高的国家之一，但尚未报道幽门螺杆菌基因多样性与胃癌之间的关联。这项研究的目的是确定幽门螺杆菌cagA和vacA基因的流行，并研究其是否可能与哥斯达黎加的萎缩性胃炎（AG）和胃癌（GC）相关。

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来源
《Helicobacter》 |2007年第5期|共6页
作者
Sergio A. Con; Hiroaki Takeuchi; Ana L. Valerin; Reinaldo Con-Wong; Gil R. Con-Chin; Vicky G. Con-Chin; Mitsuaki Nishioka; Fernando Mena; Fernando Brenes; Nobufumi Yasuda;
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正文语种 eng
中图分类微生物学;
关键词
Helicobacter pylori; atrophic gastritis; gastric cancer; Costa Rica;

机译：幽门螺杆菌;萎缩性胃炎;胃癌;哥斯达黎加;

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1. Diversity of Helicobacter pylori cagA and vacA Genes in Costa Rica: Its Relationship with Atrophic Gastritis and Gastric Cancer [J] . Sergio A. Con, Hiroaki Takeuchi, Ana L. Valerin, Helicobacter . 2007,第5期

机译：哥斯达黎加的幽门螺杆菌cagA和vacA基因多样性：与萎缩性胃炎和胃癌的关系
2. Diversity of Helicobacter pylori vacA andcagA Genes and Relationship to VacA and CagA Protein Expression, Cytotoxin Production, and Associated Diseases [J] . Jochen Rudi, Christof Kolb, Matthias Maiwald, Journal of Clinical Microbiology . 1998,第4期

机译：幽门螺杆菌vacA和cagA基因的多样性及其与VacA和CagA蛋白表达，细胞毒素产生及相关疾病的关系
3. The relationship between polymorphism in HLA-A, HLA-B, HLA-DR and DQ genes of gastric cancer and duodenal ulcer patients with Helicobacter pylori cagA/vacA s1m1 genotype [J] . Kocazeybek B. S., Kirmusaoglu S., Yilmaz E., Helicobacter . 2019,第Suppla1期

机译：胃癌HLA-A，HLA-B，HLA-DR和DQ基因多态性与幽门螺杆菌CAGA / VACA S1M1基因型的胃癌和十二指肠溃疡患者的关系
4. Molecular Diagnosis of Helicobacter pylori Infection and Risk Factor of the Presence of cagA and vacA Genes [C] . Hassan A, Dwidar N, Helaly G Incorporating of the Australian Society for Biochemistry and Molecular Biology Combio . 2009

机译：幽门螺杆菌感染的分子诊断和CAGA和VACA基因存在的危险因素
5. Helicobacter pylori stimulates gastric cancer cell motility through a combination of CagA-dependent and CagA-independent signaling [D] . Snider, Jared Lee 2008

机译：幽门螺杆菌通过依赖于CagA和独立于CagA的信号传导刺激胃癌细胞的运动
6. Diversity of Helicobacter pylori vacA and cagA Genes and Relationship to VacA and CagA Protein Expression Cytotoxin Production and Associated Diseases [O] . Jochen Rudi, Christof Kolb, Matthias Maiwald, 1998

机译：幽门螺杆菌vacA和cagA基因的多样性及其与VacA和CagA蛋白表达细胞毒素产生及相关疾病的关系
7. Helicobacter pylori vacA and cagA genotype diversity and interferon gamma expression in patients with chronic gastritis and patients with gastric cancer [O] . D.N. Martínez-Carrillo, J. Atrisco-Morales, R. Hernández-Pando, 2014

机译：慢性胃炎和胃癌患者幽门螺杆菌vaca和caga基因型多样性及干扰素γ的表达

Diversity of Helicobacter pylori cagA and vacA Genes in Costa Rica: Its Relationship with Atrophic Gastritis and Gastric Cancer

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