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Biomarkers in heart failure. Preface.

机译:心力衰竭中的生物标志物。前言。

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摘要

Until recently, the classification of heart failure (HF) has focused on the anatomic cause of failure of the cardiac pump (eg, valvular heart disease, hypertension, chronic coronary artery disease, and so forth), the pathophysiology (eg, reduced or normal ejection fraction), and the clinical features (eg, the acuity and severity of the HF). A biomarker profile can be a valuable addition to this approach. The major classes of biomarkers for HF discussed in this issue of Heart Failure Clinics are usually considered individually, as they were done so expertly in this issue. However, investigators are finding increasingly that a multimarker strategy may be useful in refining risk stratification in patients who have acute coronary syndrome,1 and there is a growing interest in utilizing this approach in HF as well.
机译:直到最近,心力衰竭(HF)的分类都集中在心脏泵衰竭的解剖原因(例如瓣膜性心脏病,高血压,慢性冠状动脉疾病等),病理生理学(例如降低或正常)上。射血分数)和临床特征(例如,HF的敏锐度和严重程度)。生物标志物谱可以是该方法的有价值的补充。在本期《心力衰竭诊所》中讨论的HF的主要生物标志物类别通常会被单独考虑,因为它们在本期中是经过专门研究的。但是,研究人员越来越发现,多标记策略可能有助于改善急性冠脉综合征的患者的危险分层[1],并且在HF中使用这种方法的兴趣也越来越高。

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