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首页> 外文期刊>Heart and vessels: An international journal >Association between smoking habits and severity of coronary stenosis as assessed by coronary computed tomography angiography
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Association between smoking habits and severity of coronary stenosis as assessed by coronary computed tomography angiography

机译：吸烟习惯与冠状动脉狭窄程度之间的关联，通过冠状动脉计算机断层扫描血管造影术评估

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Smoking promotes arteriosclerosis and is one of the most important coronary risk factors. However, few studies have investigated the association between smoking habits and the severity of coronary stenosis as assessed by coronary computed tomography angiography (CTA). We enrolled 416 patients [165/251 = smoker (past and current)on-smoker)]. They had all undergone CTA and either were clinically suspected of having coronary artery disease (CAD) or had at least one cardiovascular risk factor. We divided the patients into smoking and non-smoking groups, and evaluated the presence of CAD, the number of significantly stenosed coronary vessels (VD), and the Gensini score as assessed by CTA in the two groups. The incidence of CAD, VD, the Gensini score, and coronary calcification score in the smoking group were all significantly greater than those in the non-smoking group (CAD, p = 0.009; VD, p = 0.003; Gensini score, p = 0.007; coronary calcification score, p = 0.01). Pack-year was significantly associated with VD and the Gensini score, and was strongly associated with multi-vessel disease (2- and 3-VD) (p < 0.05), whereas the duration of cessation in past smokers was not associated with VD or the Gensini score. Pack-year, but not the duration of cessation, may be the most important factor that was associated with the severity of coronary stenosis in terms of VD and the Gensini score.
机译：吸烟会促进动脉硬化，是最重要的冠状动脉危险因素之一。但是，很少有研究调查吸烟习惯与冠状动脉狭窄程度之间的关联，如通过冠状动脉计算机断层血管造影术（CTA）评估的那样。我们招募了416名患者[165/251 =吸烟者（过去和现在）/不吸烟）。他们都接受了CTA治疗，或者临床上怀疑患有冠心病（CAD）或至少患有一种心血管危险因素。我们将患者分为吸烟组和非吸烟组，并评估了两组患者是否存在CAD，冠状动脉明显狭窄的数量以及通过CTA评估的Gensini评分。吸烟组的CAD，VD，Gensini评分和冠状动脉钙化评分的发生率均显着高于非吸烟组（CAD，p = 0.009; VD，p = 0.003; Gensini评分，p = 0.007 ;冠状动脉钙化评分，p = 0.01）。包年与VD和Gensini评分显着相关，并且与多支血管疾病（2-和3-VD）密切相关（p <0.05），而过去吸烟者的戒烟时间与VD或VD无关。 Gensini得分。在VD和Gensini评分方面，包年（而非停药时间）可能是与冠状动脉狭窄严重程度相关的最重要因素。

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