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Radiotherapy for liver tumors

机译:肝肿瘤放疗

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Many patients with primary hepatic malignancies present with advanced disease that is not suitable for surgical resection, orthotopic liver transplantation, or radiofrequency ablation. Outcomes are particularly dismal in patients with large, unresectable tumors and/or tumor venous thrombosis. Liver-directed radiotherapy, including stereotactic body radiotherapy (SBRT), is able to treat a variety of tumor sizes and tumors with venous involvement and has demonstrated excellent safety and control outcomes. SBRT should be considered a standard option in patients with early-stage hepatocellular carcinoma who are not candidates for surgical resection, orthotopic liver transplantation or radiofrequency ablation. SBRT should be strongly considered in patients with larger tumors and/or tumors with tumor venous thrombosis who have adequate liver function. Radiotherapy should remain a focus of hepatocellular carcinoma research.
机译:许多原发性肝恶性肿瘤患者患有晚期疾病,不适合手术切除,原位肝移植或射频消融治疗。在患有无法切除的大肿瘤和/或肿瘤静脉血栓形成的患者中,结果尤其令人沮丧。包括立体定向身体放射疗法(SBRT)在内的肝定向放射疗法能够治疗多种肿瘤大小和静脉受累的肿瘤,并已显示出出色的安全性和控制效果。对于不适合手术切除,原位肝移植或射频消融的早期肝细胞癌患者,SBRT应该被视为标准选择。对于具有较大肝功能的较大肿瘤和/或肿瘤静脉血栓形成的患者,应强烈考虑使用SBRT。放射治疗应仍然是肝细胞癌研究的重点。

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