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首页> 外文期刊>Hepato-gastroenterology. >Ano-neorectal function using manometry on patients after restorative proctocolectomy and ileal J-pouch anal anastomosis for ulcerative colitis in children
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Ano-neorectal function using manometry on patients after restorative proctocolectomy and ileal J-pouch anal anastomosis for ulcerative colitis in children

机译：压力性直肠结肠切除术和回肠J型袋肛门吻合术治疗儿童溃疡性结肠炎后使用测压法的无肾结直肠功能

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Background/Aims: The purpose of this study was to clarify the ano-neorectal functions in pediatric patients with soiling at a short period and without soiling at a long period after restorative colectomy and ileal J-pouch anal anastomosis (IPAA) for ulcerative colitis (UC). Methodology: Ten patients after IPAA for UC in childhood were mamometrically studied, aged 10 to 16 years (mean, 13.9 years). Patients after IPAA with ileostomy closure were studied at 6 months (Group A; all patients had soiling) and 3 years after ileostomy closure (Group B; all patients showed continence). Group C served as controls and consisted of 12 subjects (aged 12 to 16 years, mean, 14.8). Results: Maximum anal sphincter pressure at rest and maximum anal sphincter pressure during voluntary contraction were significantly lower in group A than in groups B and C. Minimum neorectal sensory threshold volume in group A was significantly higher than in groups B and C (p<0.01). Maximum neorectal tolerated threshold volumes and neorectal compliances, and positive rates of neorectoanal inhibitory reflex, showed no significant difference among the groups. Conclusions: Patients with soiling at 6 months after IPAA showed anal sphincter dysfunction and neorectal sensory dysfunction. The IPAA may cause damage to the ano-neorectal apparatus during rectal mobilization due to the short rectal cuff and mucosectomy.
机译：背景/目的：本研究的目的是弄清在进行结肠结肠切除术和回肠J袋肛门吻合术（IPAA）治疗溃疡性结肠炎后短期内弄脏而长期不弄脏的小儿患者的负性肾结直肠功能（ UC）。方法：对10例儿童进行IPAA UC UC治疗后，对其年龄进行了X线检查，年龄10至16岁（平均13.9岁）。在接受IPAA的患者中，在回肠造口术结束后6个月（A组;所有患者均已弄脏）和回肠造口术闭合后3年（B组;所有患者均出现尿失禁）进行了研究。 C组为对照组，由12名受试者组成（年龄12至16岁，平均14.8）。结果：A组的静止时最大肛门括约肌压力和自发性收缩期间的最大肛门括约肌压力显着低于B和C组.A组的最小直肠直肠感觉阈值量显着高于B和C组（p <0.01 ）。各组之间最大的新直肠耐受阈值量和新直肠顺应性以及新直肠抑制反射的阳性率没有显着差异。结论：IPAA术后6个月出现脏污的患者表现出肛门括约肌功能障碍和新直肠感觉功能障碍。由于直肠袖口短和粘膜切除术，在直肠动员过程中，IPAA可能会损坏阳极-结直肠装置。

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