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Relation between the risk of gallstone pancreatitis and characteristics of gallstone in Korea.

机译:韩国胆结石胰腺炎的风险与胆结石特征之间的关系。

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BACKGROUND/AIMS: Pancreatitis is a serious complication of patients with gallstones. However, risk factors of gallstone pancreatitis were unpredictable until recently. In Korea, characteristics of gallstones are different from Western countries. The present study was designed to determine differences in the risk of gallstone pancreatitis and characteristics of gallstones in Korean patients. METHODOLOGY: Clinical data were collected on patients undergoing laparoscopic cholecystectomy. The physical characteristics of gallstones recovered at surgery were also recorded. Patients with gallstone pancreatitis were compared with patients who had uncomplicated biliary pain. RESULTS: In a logistic regression model, acute gallstone pancreatitis was associated with a stone diameter of less than 5 mm (odds ratio: 3.3695; P = 0.0352) and with stone number of more than 20 (odds ratio: 3.8686; P = 0.0361). No other variable, including pigment stone, age, and sex, remained statistically significant in the adjusted analysis (P > 0.05). CONCLUSIONS: Patients with at least 1 gallstone smaller than 5 mm in diameter and stone number more than 20 each have a more than 3-fold increased risk of presenting with acute gallstone pancreatitis. The composition of gallstones, especially pigment stones, was not an important risk factor in gallstone pancreatitis in Korean patients with stones having a different composition than those from Western countries.
机译:背景/目的:胰腺炎是胆结石患者的严重并发症。然而,直到最近,胆石性胰腺炎的危险因素仍无法预测。在韩国,胆结石的特征与西方国家不同。本研究旨在确定韩国患者胆石性胰腺炎的风险和胆石特征的差异。方法:收集了腹腔镜胆囊切除术患者的临床数据。还记录了在手术中恢复的胆结石的物理特征。将胆石性胰腺炎患者与单纯胆汁痛患者进行比较。结果:在逻辑回归模型中,急性胆结石性胰腺炎的结石直径小于5 mm(比值:3.3695; P = 0.0352),结石数目大于20(比值比:3.8686; P = 0.0361)。 。在调整后的分析中,没有其他变量(包括色素结石,年龄和性别)在统计学上保持显着性(P> 0.05)。结论:至少有1个直径小于5毫米的胆结石且结石数目大于20的患者出现急性胆石性胰腺炎的风险增加了3倍以上。对于韩国人结石成分与西方国家不同的结石患者,胆结石,尤其是色素结石的组成并不是胆结石胰腺炎的重要危险因素。

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