Drug-induced autoimmune hepatitis caused by anti-tumor necrosis factor alpha agents.

Efe C; Purnak T; Ozaslan E; Wahlin S

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Drug-induced autoimmune hepatitis caused by anti-tumor necrosis factor alpha agents.

机译：抗肿瘤坏死因子α药物引起的药物诱发的自身免疫性肝炎。

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We read with great interest the report by Bjornsson et al.1 regarding the clinical characteristics and prognosis of patients with drug-induced autoimmune hepatitis (DIAIH). In their study, the authors described 24 patients with DIAIH resulting from nitrofur-antoin and minocycline use.Tumor necrosis factor a (TNF-a) blocking agents are drugs commonly used in the treatment of rheumatological, dermatological, and gas-troenterological autoimmune diseases. Minor abnormalities in liver function tests are relatively common with the use of anti-TNF-a agents, but the development of serious hepatic failure and the reactivation of viral hepatitis might be possible as well.

机译：我们非常感兴趣地阅读了Bjornsson等[1]关于药物诱发的自身免疫性肝炎（DIAIH）患者的临床特征和预后的报告。在他们的研究中，作者描述了24位因使用呋喃丁酮和米诺环素而导致的DIAIH患者。肿瘤坏死因子a（TNF-a）阻断剂是通常用于治疗风湿病，皮肤病和胃肠道自身免疫性疾病的药物。肝功能检查中的轻微异常现象在使用抗TNF-a药剂时相对普遍，但严重的肝衰竭和病毒性肝炎的再激活也可能发生。

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《Hepatology: Official Journal of the American Association for the Study of Liver Diseases》 |2010年第6期|共2页
作者
Efe C; Purnak T; Ozaslan E; Wahlin S;
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正文语种 eng
中图分类消化系及腹部疾病;
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1. Drug-induced autoimmune hepatitis caused by anti-tumor necrosis factor alpha agents. [J] . Efe C, Purnak T, Ozaslan E, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2010,第6期

机译：抗肿瘤坏死因子α药物引起的药物诱发的自身免疫性肝炎。
2. New Onset Autoimmune Hepatitis during Anti-Tumor Necrosis Factor-Alpha Treatment in Children [J] . Amanda Ricciuto, Binita M. Kamath, Thomas D. Walters, The Journal of pediatrics . 2018,第期

机译：新发起自身免疫性肝炎在儿童抗肿瘤坏死因子α治疗中
3. Autoimmune hepatitis and anti-tumor necrosis factor alpha therapy: A single center report of 8 cases [J] . Rodrigues Susana, Lopes Susana, Magro Fernando, World journal of gastroenterology : . 2015,第24期

机译：自身免疫性肝炎和抗肿瘤坏死因子α疗法：8例单中心报告
4. Prevalence of autoantibodies and the risk of autoimmune thyroid disease in children with chronic hepatitis C virus (HCV) infection treated with alpha-interferon [C] . S. GEHRING, E. LAUSCH, U. KULLMER, Falk Symposium . 2002

机译：α-干扰素治疗慢性丙型肝炎病毒（HCV）感染儿童自身抗体和自身免疫性甲状腺疾病风险的患病率
5. Mechanisms of hepatocellular apoptosis induced by trovafloxacin-tumor necrosis factor-alpha interaction: An in vitro model of idiosyncratic drug-induced liver injury. [D] . Beggs, Kevin Michael. 2013

机译：曲伐沙星-肿瘤坏死因子-α相互作用诱导的肝细胞凋亡机制：特异药物诱导的肝损伤的体外模型。
6. Autoimmune hepatitis and anti-tumor necrosis factor alpha therapy: A single center report of 8 cases [O] . Susana Rodrigues, Susana Lopes, Fernando Magro, 2015

机译：自身免疫性肝炎和抗肿瘤坏死因子α疗法：8例单中心报告
7. Drug-induced autoimmune hepatitis caused by anti-tumor necrosis factor α agents [O] . Cumali Efe, Tugrul Purnak, Ersan Ozaslan, 2010

机译：药物诱导的自身免疫性肝炎由抗肿瘤坏死因子α剂引起的
8. Interdependence of the Radioprotective Effects of Human Recombinant Interleukin 1alpha, Tumor Necrosis Factor alpha, Granulocyte Colony-Stimulating Factor, and Murine Recombinant Granulocyte-Macrophage Colony-Stimulating Factor [R] . Neta, R., Oppenheim, J. J., Douches, S. D. 1988

机译：人重组白细胞介素1α，肿瘤坏死因子α，粒细胞集落刺激因子和小鼠重组粒细胞 - 巨噬细胞集落刺激因子的辐射保护作用的相互依赖性

Drug-induced autoimmune hepatitis caused by anti-tumor necrosis factor alpha agents.

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