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首页> 外文期刊>Hepatology: Official Journal of the American Association for the Study of Liver Diseases >Ursodeoxycholic acid in primary sclerosing cholangitis: If withdrawal is bad, then administration is good (right?)
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Ursodeoxycholic acid in primary sclerosing cholangitis: If withdrawal is bad, then administration is good (right?)

机译:原发性硬化性胆管炎中的熊去氧胆酸:如果停药不好,则给药良好(对吗?)

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摘要

Primary sclerosing cholangitis (PSC) is a chronic, idiopathic, cholestatic liver disease characterized by biliary inflammation and periductal fibrosis. Unlike most other cholestatic liver diseases, PSC affects individuals of essentially all ages and racial backgrounds, remains etiopathogenically perplexing, and lacks established medical therapy despite extensive laboratory-based investigation, translational research, and clinical trials.It is on this basis that PSC has, regrettably, come to be regarded as the "black box" of liver disease.
机译:原发性硬化性胆管炎(PSC)是一种慢性,特发性胆汁淤积性肝病,其特征是胆道炎症和导管周围纤维化。与大多数其他胆汁淤积性肝病不同,尽管PSC进行了广泛的实验室研究,转化研究和临床试验,但PSC影响着几乎所有年龄和种族背景的个体,在病因上仍然令人困惑,并且缺乏既定的医学治疗方法。遗憾的是,它被视为肝脏疾病的“黑匣子”。

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