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Be antibiotic wise with mastitis

机译:对乳腺炎要慎用抗生素

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How often do you want to switch antibiotic tubes . . . after a couple of treatments if a cow with mastitis still has clots and/or flakes that haven't gone away? It's easy to think the antibiotic is not working and something else might work better.However, remember there are only seven FDA-approved intramam-mary (IMM) formulations for treating lactating cows in the U.S. and six of them are beta-lactam antibiotics. That means those six are very similar in mode of action and spectrum of activity (pirlimycin is the nonbeta-lactam choice and only has activity against gram-positive organisms). Thus, there is not much pharmacologic justification to altering the treatment path once it has been decided upon and initiated.
机译:您想多久更换一次抗生素管。 。 。经过几次治疗后,患有乳腺炎的母牛是否仍有血块和/或薄片尚未消失?人们很容易认为这种抗生素不能起作用,而其他的方法可能会更好。但是,请记住,在美国,只有七种FDA批准的用于治疗泌乳母牛的母乳内制剂(IMM),其中六种是β-内酰胺类抗生素。这意味着这六个在作用方式和活性谱上非常相似(吡p霉素是非β-内酰胺的选择,仅对革兰氏阳性生物有活性)。因此,一旦决定并开始改变治疗途径,就没有太多的药理学依据。

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