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首页> 外文期刊>Trends in Ecology & Evolution >Cancer: A missing link in ecosystem functioning?
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Cancer: A missing link in ecosystem functioning?

机译:癌症:生态系统功能的缺失环节?

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摘要

Cancer is a disease that affects the majority of metazoan species and, before directly causing host death, is likely to influence the competitive abilities of individuals, their susceptibility to pathogens, their vulnerability to predators, and their ability to disperse. Despite the potential importance of these ecological impacts, cancer is rarely incorporated into model ecosystems. We describe here the diversity of ways in which oncogenic phenomena, from precancerous lesions to generalized metastatic cancers, may affect ecological processes that govern biotic interactions. We argue that oncogenic phenomena, despite their complexity, can have significant and sometimes predictable ecological consequences. Our aim is to provide a new perspective on the ecological and evolutionary significance of cancer in wildlife, and to stimulate research on this topic.
机译:癌症是一种影响大多数后生动物的疾病,在直接导致宿主死亡之前,它很可能会影响个体的竞争能力,对病原体的敏感性,对捕食者的脆弱性以及扩散能力。尽管这些生态影响具有潜在的重要性,但癌症很少被纳入模型生态系统。我们在这里描述从癌前病变到全身转移性癌的致癌现象可能影响控制生物相互作用的生态过程的多种方式。我们认为,致癌现象尽管复杂,却可能产生重大的,有时甚至可预测的生态后果。我们的目的是为野生生物中癌症的生态和进化意义提供新的观点,并激发对此主题的研究。

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