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首页> 外文期刊>Human Biology: Official Publication of the Human Biology Council >Genetics and the history of the Samaritans: Y-chromosomal microsatellites and genetic affinity between samaritans and cohanim
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Genetics and the history of the Samaritans: Y-chromosomal microsatellites and genetic affinity between samaritans and cohanim

机译：撒玛利亚人的遗传和历史：Y染色体微卫星以及撒玛利亚人和cohanim之间的遗传亲和力

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The Samaritans are a group of some 750 indigenous Middle Eastern people, about half of whom live in Holon, a suburb of Tel Aviv, and the other half near Nablus. The Samaritan population is believed to have numbered more than a million in late Roman times but less than 150 in 1917. The ancestry of the Samaritans has been subject to controversy from late Biblical times to the present. In this study, liquid chromatography/electrospray ionization/quadrupole ion trap mass spectrometry was used to allelotype 13 Y-chromosomal and 15 autosomal microsatellites in a sample of 12 Samaritans chosen to have as low a level of relationship as possible, and 461 Jews and non-Jews. Estimation of genetic distances between the Samaritans and seven Jewish and three non-Jewish populations from Israel, as well as populations from Africa, Pakistan, Turkey, and Europe, revealed that the Samaritans were closely related to Cohanim. This result supports the position of the Samaritans that they are descendants from the tribes of Israel dating to before the Assyrian exile in 722-720 BCE. In concordance with previously published single-nucleotide polymorphism haplotypes, each Samaritan family, with the exception of the Samaritan Cohen lineage, was observed to carry a distinctive Y-chromosome short tandem repeat haplotype that was not more than one mutation removed from the six-marker Cohen modal haplotype.
机译：撒玛利亚人由大约750名中东原住民组成，其中大约一半生活在特拉维夫郊区的Holon，另一半居住在纳布卢斯附近。据信撒玛利亚人的数量在罗马晚期已超过一百万，但在1917年不到150。从圣经晚期到现在，撒玛利亚人的祖先一直受到争议。在这项研究中，使用液相色谱/电喷雾电离/四极杆离子阱质谱法对12个撒玛利亚人样品中的13种Y染色体和15种常染色体微卫星进行了等位基因分析，这些样品的亲缘关系尽可能低，461名犹太人和非犹太人犹太人估计撒玛利亚人与来自以色列的七个犹太人和三个非犹太人以及非洲，巴基斯坦，土耳其和欧洲的人口之间的遗传距离，表明撒玛利亚人与科哈尼姆密切相关。这一结果支持了撒玛利亚人的立场，即他们是以色列支派的后裔，可追溯到公元前722-720年亚述流亡之前。与先前发布的单核苷酸多态性单倍型一致，除Samaritan Cohen谱系外，每个Samaritan家族均携带独特的Y染色体短串联重复单倍型，该突变不超过从六个标记中去除的一个突变科恩模态单倍型。

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