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Safety and immunogenicity of a live attenuated mumps vaccine A phase I clinical trial

机译:减毒腮腺炎活疫苗A期临床试验的安全性和免疫原性

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Background: Mumps, a communicable, acute and previously well-controlled disease, has had recent and occasional resurgences in some areas.Methods; A randomized, double-blind, controlled and multistep phase I study of an F-genotype attenuated mumps vaccine produced in human diploid cells was conducted. A total of 300 subjects were enrolled and divided into 4 age groups: 16-60 years, 5-16 years, 2-5 years and 8-24 months.
机译:背景:流行性腮腺炎是一种传染性,急性和先前得到良好控制的疾病,最近在某些地区出现了偶发性复发。对人二倍体细胞中产生的F基因型减毒腮腺炎疫苗进行了随机,双盲,对照和多步I期研究。共有300名受试者入选,分为4个年龄段:16-60岁,5-16岁,2-5岁和8-24个月。

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