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首页> 外文期刊>Hypertension in pregnancy: Official journal of the International Society for the Study of Hypertension in Pregnancy >Diastolic function in pregnant patients with cardiac symptoms diastolic function in pregnancy
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Diastolic function in pregnant patients with cardiac symptoms diastolic function in pregnancy

机译：患有心脏症状的孕妇患者的舒张功能孕期舒张功能

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Objective. Dyspnea on exertion and peripheral edema occur routinely during normal gestational stage, making early diagnosis of congestive heart failure (CHF) during pregnancy difficult. Abnormal left ventricular (LV) diastolic function may be associated with dyspnea on exertion and peripheral edema, and brain natriuretic peptide (BNP) correlates with volume overload in nonpregnant populations. We tested the hypothesis that abnormal echocardiographic diastolic parameters and elevated BNP correlate in symptomatic pregnant patients. Methods. Sixty-six gravidas presented to an Obstetric Cardiology Clinic were analyzed. Data including symptoms of CHF, BNP, and maternal and gestational ages were recorded. Echocardiograms were reviewed to measure the diastolic parameters E, A, e′, and a′ wave velocities and left atrial volume index (LAVI). Logistic regression was performed to characterize the relationship between diastolic parameters and BNP. Results. Among the 66 pregnant patients included in the analysis, only 6 were found to have significant LV systolic dysfunction. LAVI, E, and E/e′ ratio correlated positively with BNP in this symptomatic population (p = 0.008, 0.007, and 0.002, respectively). Conclusions. Abnormal diastolic parameters that represent increased LV filling pressures correlated with higher BNP levels in pregnant patients with symptoms of CHF. This suggests that symptoms may be due to diastolic dysfunction, and BNP levels may identify elevated LV filling pressures in symptomatic pregnant patients.
机译：目的。劳累性呼吸困难和周围性水肿通常在正常妊娠期发生，使怀孕期间充血性心力衰竭（CHF）的早期诊断变得困难。左心室（LV）舒张功能异常可能与运动和周围水肿引起的呼吸困难有关，而脑钠肽（BNP）与非妊娠人群的容量超负荷有关。我们检验了有症状孕妇的超声心动图舒张功能异常和BNP升高相关的假说。方法。分析了向产科心脏病诊所提供的66例孕妇。记录包括CHF，BNP症状以及孕产妇和胎龄的数据。超声心动图检查以测量舒张期参数E，A，e'和a'的波速和左心房容积指数（LAVI）。进行逻辑回归分析以表征舒张压参数与BNP之间的关系。结果。分析中包括的66名孕妇中，只有6名患有严重的LV收缩功能障碍。在有症状人群中，LAVI，E和E / e'比与BNP正相关（分别为p = 0.008、0.007和0.002）。结论。代表患有CHF症状的孕妇，舒张压参数异常代表左室充盈压升高与BNP水平升高相关。这表明症状可能是由于舒张功能障碍所致，而BNP水平可确定有症状孕妇的左室充盈压升高。

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