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A Not-So-Modest Proposal That a 'Modest' Increase in Aldosterone Causes Hypertension and More

机译:一个不太适度的建议,醛固酮的“适度”增加会导致高血压和更多

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摘要

Whether primary aldosteronism is as widespread as some believe, a topic debated recently in this journal by Calhoun and Kaplan, may not be as relevant as whether the commonly observed prevailing level of aldosterone is too high for the amount of sodium that we consume. I would like to make the case here (with help from a Nobel Laureate) that the usual level of aldosterone contributes to the development of hypertension in many people, indeed, possibly many more than even the most generous estimate for the prevalence of primary aldosteronism
机译:Calhoun和Kaplan最近在该杂志上讨论了一个话题,即原发性醛固酮增多症是否像某些人所认为的那样广泛传播,可能并不像通常观察到的醛固酮普遍存在的水平对于我们消耗的钠的量过高那样重要。我想在此说明这一点(在诺贝尔奖获得者的帮助下),正常的醛固酮水平对许多人的高血压有贡献,的确可能甚至超过对原发性醛固酮增多症的最慷慨的估计。

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