...
首页> 外文期刊>Human Pathology >Characterization of the presence of Foxp3(+) T cells from patients with different clinical forms of Chagas' disease.
【24h】

Characterization of the presence of Foxp3(+) T cells from patients with different clinical forms of Chagas' disease.

机译:具有不同临床形式的恰加斯氏病患者的Foxp3(+)T细胞的存在特征。

获取原文
获取原文并翻译 | 示例
           

摘要

Chagas' disease is a parasitic infection caused by the protozoan Trypanosoma cruzi that affects approximately 12 to 14 million people in Central and South America. This infection has a variable clinical course, with most individuals with the indeterminate form remaining free of alterations. Approximately 30% of the patients in the chronic phase of the disease develop the cardiac clinical form [1]. This form has a wide range of symptoms that range from mild alterations to severe heart damage. The myocardium of patients exhibiting chronic cardiomyopathy usually shows lymphocytic myocarditis with numerous degrees of myocardial necrosis, reparative fibrosis, and myocardial hypertrophy. The patho-genesis of the chagasic cardiomyopathy is still not fully understood, and the data available are also controversial. Most investigators believe that immunologic reactions play a fundamental role in this pathological process [2,3],
机译:恰加斯氏病是由原生动物克鲁斯锥虫引起的寄生虫感染,影响中美洲和南美洲的约12至1400万人。这种感染具有可变的临床过程,大多数具有不确定形式的个体保持无变化。在该疾病的慢性期中,大约有30%的患者发展为心脏临床形式[1]。这种形式的症状范围很广,从轻度改变到严重的心脏损害。表现出慢性心肌病的患者的心肌通常表现为淋巴细胞性心肌炎,并伴有多种程度的心肌坏死,修复性纤维化和心肌肥大。尚无关于chagasic型心肌病的发病机制,可用数据也有争议。大多数研究人员认为,免疫反应在这一病理过程中起着根本性的作用[2,3],

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号