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首页> 外文期刊>Human psychopharmacology: clinical and experimental >Fibromyalgia: a complex syndrome requiring a multidisciplinary approach.
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Fibromyalgia: a complex syndrome requiring a multidisciplinary approach.

机译：纤维肌痛：一种复杂的综合症，需要采取多学科的方法。

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Fibromyalgia is a pain syndrome which is not due to tissue damage or inflammation and is thus fundamentally different from rheumatic disorders and many other pain conditions. In addition to widespread pain it is associated with a range of other symptoms such as sleep disturbance, fatigue, cognitive disturbance, stiffness and depressive symptoms. A number of multidisciplinary therapeutic programmes involving education, exercise and cognitive therapy have been shown to be effective in bringing relief. The various medications that are currently being developed for the treatment of fibromyalgia are based on different mechanistic approaches. In particular, serotonin noradrenaline reuptake inhibitors (SNRI) such as duloxetine and milnacipran and alpha2-delta receptor ligands such as pregabalin have been shown, in a variety of placebo-controlled studies, to bring significant relief from pain and other symptoms. The complex symptomatology of fibromyalgia will, however, continue to require a multidisciplinary approach including education and exercise in addition to drug therapy to achieve the most efficient management of fibromyalgia.
机译：纤维肌痛是一种疼痛综合征，它不是由于组织损伤或炎症引起的，因此与风湿性疾病和许多其他疼痛状况根本不同。除了广泛的疼痛外，它还伴有一系列其他症状，例如睡眠障碍，疲劳，认知障碍，僵硬和抑郁症状。事实证明，许多涉及教育，运动和认知疗法的多学科治疗计划可以有效地缓解疾病。当前正在开发的用于治疗纤维肌痛的各种药物是基于不同的机械方法。特别是，在各种安慰剂对照研究中，已显示5-羟色胺去甲肾上腺素再摄取抑制剂（SNRI）（例如度洛西汀和米那普仑）和α2-δ受体配体（例如普瑞巴林）可显着缓解疼痛和其他症状。然而，复杂的纤维肌痛症状学将继续需要多学科的方法，除了药物疗法外，还应包括教育和运动，以实现对纤维肌痛的最有效管理。

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