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Human brain mercury levels related to exposure to amalgam fillings

机译：人脑汞含量与汞齐填充物的暴露有关

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摘要

The safety of dental amalgam as the primary material in dental restoration treatments has been debated since its introduction. It is widely accepted that amalgam restorations continuously release elemental mercury (Hg) vapor, which is inhaled and absorbed by the body and distributed to tissues, including the brain. The aim of the present study was to investigate whether the presence of amalgam fillings is correlated with brain Hg level. The Hg levels in the parietal lobes of the brains of 32 cadavers were analyzed with an atomic absorption spectrometer with the mercury hydride system. A total of 32 brain samples were tested; of these, 10 were from cadavers with amalgam fillings, while 22 of them were amalgam free. Hg was detected in 60.0% (6 of 10) of the samples in the amalgam group and in 36.3% (8 of 22) in the amalgam-free group. The average Hg level of the amalgam group was 0.97 ± 0.83 μg/g (minimum: 0.3 μg/g and maximum: 2.34 μg/g), and in the amalgam-free group, it was 1.06 ± 0.57 μg/g (minimum: 0.17 μg/g and maximum: 1.76 μg/g). The results of the present study showed no correlation between the presence of amalgam fillings and brain Hg level.
机译：自从引入牙科用汞合金作为牙科修复治疗的主要材料，其安全性一直受到争议。汞合金修复体不断释放元素汞（Hg）蒸气，这种蒸气被人体吸入并吸收并分布到包括大脑在内的组织中，这一点已被广泛接受。本研究的目的是调查汞合金填充物的存在是否与脑汞水平相关。使用氢化汞系统，通过原子吸收光谱仪分析了32具尸体大脑顶叶的Hg水平。总共测试了32个脑样本。其中，有10名来自带有汞合金填充物的尸体，而其中有22名没有汞合金。在汞合金组中，有60.0％（10个中的6个）中检测到汞，在无汞合金组中，有36.3％（22个中的8个）中检测到了汞。汞齐组的平均Hg水平为0.97±0.83μg/ g（最小值：0.3μg/ g，最大值：2.34μg/ g），无汞组为1.06±0.57μg/ g（最小值： 0.17μg/ g和最大值：1.76μg/ g）。本研究的结果表明，汞合金填充物的存在与脑汞水平之间没有相关性。

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