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首页> 外文期刊>Human and Experimental Toxicology >The relationship between environmental exposure to cadmium and lead and blood selenium concentration in randomly selected population of children inhabiting industrial regions of Silesian Voivodship (Poland)
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The relationship between environmental exposure to cadmium and lead and blood selenium concentration in randomly selected population of children inhabiting industrial regions of Silesian Voivodship (Poland)

机译：居住在西里西亚省（波兰）工业区的儿童中随机选择的人口中镉和铅的环境暴露与血硒浓度的关系

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This study aimed at determining the relationship between environmental exposure to lead (Pb) and cadmium (Cd) and blood selenium (Se) concentration in randomly selected population of children inhabiting the industrial regions of Silesian Voivodship, Poland. The study was conducted on a group of consecutive randomly selected 349 children aged below 15 years and inhabiting the industrial regions in Upper Silesia. The examined variables included whole blood Cd concentration (Cd-B), whole blood Pb concentration (Pb-B) and whole blood Se concentration (Se-B). The concentration of Cd-B, Pb-B and Se-B in the studied group of children amounted to 0.26 ± 0.14, 37.62 ± 25.30 and 78.31 ± 12.82 μg/L, respectively. In the entire examined group a statistically significant negative linear relationship was noted between Pb-B and Se-B (r = -0.12, p < 0.05). Also, a statistically insignificant negative correlation was detected between Cd-B and Se-B (r = -0.02, p > 0.05) and a statistically insignificant positive correlation between Pb-B and Cd-B (r = 0.08, p > 0.05). A multivariate backward stepwise regression analysis demonstrated that in the studied group of children higher Pb-B and a more advanced age-represented independent risk factors for a decreased Se-B. Environmental exposure to Pb may represent an independent risk factor for Se deficit in blood of the studied population of children. In children, the lowered Se-B may create one of the mechanisms in which Pb unfavourably affects human body.
机译：这项研究旨在确定居住在波兰西里西亚省工业区的儿童中随机抽取的儿童中铅，镉和镉的环境暴露与血硒浓度的关系。该研究是对一组连续随机选择的349名15岁以下且居住在上西里西亚工业区的儿童进行的。检查的变量包括全血Cd浓度（Cd-B），全血Pb浓度（Pb-B）和全血Se浓度（Se-B）。研究组儿童中Cd-B，Pb-B和Se-B的浓度分别为0.26±0.14、37.62±25.30和78.31±12.82μg/ L。在整个检查组中，Pb-B和Se-B之间存在统计学上显着的负线性关系（r = -0.12，p <0.05）。另外，在Cd-B和Se-B之间检测到无统计学意义的负相关（r = -0.02，p> 0.05），在Pb-B和Cd-B之间检测到无统计学意义的正相关（r = 0.08，p> 0.05） 。多元后向逐步回归分析表明，在研究组的儿童中，较高的Pb-B和较高的年龄代表了降低Se-B的独立危险因素。环境中的Pb暴露可能代表所研究儿童血液中硒缺乏的独立危险因素。在儿童中，Se-B降低可能是Pb不利地影响人体的一种机制。

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