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Patterns of Perineural Tumor Spread in Head and Neck Cancer

机译:头颈部癌的神经周围肿瘤扩散模式

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Perineural tumor spread (PNS) is a mode of neoplastic spread whereby tumor cells use neural conduits to escape the borders of a primary tumor. MRI is generally favored over CT for evaluating PNS, and findings include obliteration of fat within skull base foramina, enlargement and enhancement of the involved nerves, and enlargement and destruction of the bony foramina. Careful examination of the entire course of the nerve allows detection of skip lesions. Recognition of the complete extent of PNS is crucial for correct treatment because it facilitates both surgical and radiotherapy targeting of entire extent of disease.
机译:神经周围肿瘤扩散(PNS)是肿瘤扩散的一种方式,肿瘤细胞利用神经导管逃避原发性肿瘤的边界。 MRI在评估PNS方面通常比CT更受青睐,其发现包括消除颅底孔内的脂肪,累及受累神经的增大和增强,以及骨孔的增大和破坏。仔细检查整个神经过程可以发现跳跃性病变。识别PNS的完整范围对于正确治疗至关重要,因为它有助于针对整个疾病范围的外科手术和放射疗法。

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