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首页> 外文期刊>Zoological Science >Response of a neotenic goby, ice goby (Leucopsarion petersii), to thyroid hormone and thiourea treatments
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Response of a neotenic goby, ice goby (Leucopsarion petersii), to thyroid hormone and thiourea treatments

机译：新生虾虎鱼，冰虾虎鱼（Leucopsarion petersii）对甲状腺激素和硫脲治疗的反应

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摘要

In order to clarify the mechanisms of neoteny in the ice goby (Leucopsarion petersii), we examined effects of thyroid hormone and thiourea (TU) treatments on their neotenic characteristics and the pituitary-thyroid axis. Adult ice goby were exposed to 3, 5, 3'-triiodothyronine (T3, 0.1 ppm), TU (inhibitor of thyroid hormone synthesis, 30 ppm), or the combination of the two for 2 weeks. Observations of whole body T3 levels, thyroid follicles and TSH immunoreactive cells in the pituitary suggests the presence of a functioning thyroidal system. However, all of the neotenic features did not disappear in T3-treated fish, suggesting the absence of T3 responsiveness in peripheral tissues. These results indicate the similarity between neoteny of the ice goby and obligatory-type neoteny of urodeles.
机译：为了阐明冰虾虎鱼（Leucopsarion petersii）的新生机制，我们检查了甲状腺激素和硫脲（TU）治疗对它们的新生特征和垂体-甲状腺轴的影响。将成年冰虾暴露于3、5、3'-三碘甲腺氨酸（T3，0.1 ppm），TU（甲状腺激素合成抑制剂，30 ppm）或两者的组合中暴露2周。垂体中的全身T3水平，甲状腺滤泡和TSH免疫反应性细胞的观察表明存在正常的甲状腺系统。然而，在经T3处理的鱼中，所有的先天性特征都没有消失，这表明外周组织中没有T3反应性。这些结果表明，冰虾虎鱼的新生代与乌德勒犬的强制性新生代之间存在相似性。

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