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The Repertoire of Chemical Defense Genes in the Coral Acropora digitifera Genome

机译:珊瑚指状藻基因组中的化学防御基因库

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摘要

Scleractinian corals are of fundamental ecological significance in tropical and sub-tropical shallow water. This ecological success is attributed to their ability of formation of obligate endosymbioses with dinoflagellates of the genus Symbiodinium. Nevertheless, approximately one-third of reef-building coral species are critically endangered and the remainder are under threat from the effects of climate change and local impacts. Molecular and cellular mechanisms involved in stress responses and the establishment and collapse of the symbiosis are therefore an urgent subject of research. Metazoans possess large numbers of genes that participate in response to environmental stressors, and chemical defense genes included P450 and other oxidases, various conjugating enzymes, ATP-dependent efflux transporters, oxidative detoxification proteins, as well as transcription factors that regulate these genes. Here we searched those genes in recently decoded the coral Acropora digitifera genome. We found that this genome contains a set of chemical defense genes in numbers comparable with other cnidarians and metazoans and that there are some lineage-specific gene family expansions in the coral genome. These provide information for future research into molecular mechanisms involved in coral stress responses.
机译:巩膜珊瑚在热带和亚热带浅水中具有根本的生态意义。这种生态学的成功归因于它们与共生菌属的鞭毛鞭毛形成专性内共生酶的能力。然而,大约三分之一的造礁珊瑚物种受到严重威胁,其余物种受到气候变化和当地影响的威胁。因此,涉及应激反应以及共生的建立和崩溃的分子和细胞机制是研究的紧迫课题。后生动物拥有大量参与环境应激反应的基因,化学防御基因包括P450和其他氧化酶,各种结合酶,ATP依赖性外排转运蛋白,氧化解毒蛋白以及调节这些基因的转录因子。在这里,我们搜索了最近解码的珊瑚指藻基因组中的那些基因。我们发现该基因组包含一组化学防御基因,其数量可与其他cnidarians和后生动物相媲美,并且在珊瑚基因组中有一些谱系特异性基因家族扩展。这些为将来研究涉及珊瑚胁迫反应的分子机制提供了信息。

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