Dialiumoside, an olean-18-ene triterpenoid from Dialium excelsum

Awantua A.F.; Lenta B.N.; Bogner T.; Fongang Y.F.; Ngouela S.; Wansi J.D.; Tsamo E.; Sewald N.

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Dialiumoside, an olean-18-ene triterpenoid from Dialium excelsum

机译：Dialiumoside，来自Dial高的Olean-18烯三萜类化合物

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Phytochemical investigation of the stem bark and fruits of Dialium excelsum led to the isolation of a new triterpenoid, named dialiumoside (1), together with twelve known compounds (2 - 13). The structure of the new compound as well as those of the known compounds were established by means of spectroscopic methods and by comparison with previously reported data. Compounds 1 - 13 were tested for their cytotoxic activity against the human cervix carcinoma KB-3-1 cells and the related multi drug-resistant P-gp-expressing KB-V1 cells. Compounds 1 and 13 showed weak biological activity in cytotoxicity assays while other compounds were inactive.

机译：通过对白花蛇菊茎皮和果实进行植物化学研究，可以分离出一种新的三萜类化合物，称为二ium苷（1）以及十二种已知化合物（2-13）。通过光谱方法并与先前报道的数据进行比较，确定了新化合物以及已知化合物的结构。测试化合物1-13对人宫颈癌KB-3-1细胞和相关的多药耐药性表达P-gp的KB-V1细胞的细胞毒性活性。化合物1和13在细胞毒性试验中显示出较弱的生物学活性，而其他化合物则没有活性。

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来源
《Zeitschrift fur Naturforschung, B. A Journal of Chemical Sciences》 |2011年第6期|共5页
作者
Awantua A.F.; Lenta B.N.; Bogner T.; Fongang Y.F.; Ngouela S.; Wansi J.D.; Tsamo E.; Sewald N.;
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正文语种 eng
中图分类化学;
关键词
Cytotoxicity; Dialium excelsum; Dialiumoside; KB-3-1 and KB-V1 Cells; Triterpenoids;

机译：细胞毒性;D;复方皂甙;KB-3-1和KB-V1细胞;三萜;

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1. Dialiumoside, an olean-18-ene triterpenoid from Dialium excelsum [J] . Awantua A.F., Lenta B.N., Bogner T., Zeitschrift fur Naturforschung, B. A Journal of Chemical Sciences . 2011,第6期

机译：Dialiumoside，来自Dial高的Olean-18烯三萜类化合物
2. Synthesis and Anti-HIV Activity of Lupane and Olean-18-ene Derivatives. Absolute Configuration of 19,20-Epoxylupanes by VCD [J] . Gutierrez-Nicolas Fatima, Gordillo-Roman Barbara, Oberti Juan C., Journal of natural products . 2012,第4期

机译：Lupane和Olean-18-ene衍生物的合成及其抗HIV活性。 VCD的19,20-环氧丙烷的绝对构型
3. Axillary shoot proliferation and plant regeneration in Euryodendron excelsum H. T. Chang, a critically endangered species endemic to China [J] . Shuangyan Chen, Yuping Xiong, Teng Wu, Scientific reports. . 2020,第1期

机译：Euryodendron Excelsum H.T. chang中的腋芽芽增殖和植物再生，危及濒危物种
4. Effects of Dialium guineense Based Zinc Nanoparticle Material on the Inhibition of Microbes Inducing Microbiologically Influenced Corrosion [C] . Joshua Olusegun Okeniyi, Gbadebo Samuel John, Taiwo Felicia Owoeye, Proceedings of the 3rd Pan American materials congress . 2017

机译：几内亚基于几内亚的锌纳米粒子材料对微生物诱导的微生物腐蚀的抑制作用。
5. Suppression of Mammary Tumorigenesis by a Gemini Vitamin D Analog and a Synthetic Triterpenoid. [D] . So, Jae Young. 2013

机译：双子座维生素D类似物和合成三萜类化合物抑制乳腺肿瘤的发生。
6. Antioxidant Activities of Dialium indum L. Fruit and Gas Chromatography-Mass Spectrometry (GC-MS) of the Active Fractions [O] . Muhamad Faris Osman, Norazian Mohd Hassan, Alfi Khatib, 2018

机译：Dial的抗氧化活性。水果和气相色谱-质谱法（GC-MS）的有效成分
7. Cytotoxic Triterpenoids from the Stem Barks of Dysoxylum arborescens and Dysoxylum excelsum against MCF-7 Breast Cancer Cell [O] . Achmad Zainuddin, Sylvia Rachmawati Meilanie, Darwati Darwati, 2020

机译：来自Dystoxylum arborescens和Dystoxylum Excelsum的细胞毒性三萜类化合物针对MCF-7乳腺癌细胞

Dialiumoside, an olean-18-ene triterpenoid from Dialium excelsum

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