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Control of tropical theileriosis with attenuated schizont vaccine in China

机译：中国减毒裂殖体疫苗控制热带麻疯病

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摘要

Tropical theileriosis, a tick borne disease of cattle caused by the protozoan Theileria annulata, was widely distributed in northern China Causing great economical losses before the 1980's. In the 1960's blood passaging, irradiation and in vitro Culture of parasite were used for the development of attenuated vaccine. Two lines of the schizont stage were obtained which both provided sufficient protection against tick infestation or blood challenge in experimental and field trials. A gelatin protection technique allowed storage at 4 degrees C, significantly prolonged shelf life and permitted transport without a cold chain. The vaccines were commercialized and widely administered in epidemic areas, leading to control of T annulata infection in China
机译：热带原虫病是由原生动物Theileria annulata引起的由牛传播的disease传播疾病，在中国北方广泛分布，在1980年代之前造成了巨大的经济损失。在1960年代的血液传代，辐射和体外寄生虫培养被用于开发减毒疫苗。获得了两条裂殖体阶段的品系，它们在实验和现场试验中均提供了足够的保护，以防止tick虫侵袭或血液攻击。明胶保护技术允许在4摄氏度下存储，大大延长了保质期，并且无需冷链即可运输。疫苗已经商业化并在流行地区广泛使用，从而控制了中国的棉铃虫感染

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