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Too much of a good thing: Management of BCG vaccine overdose

机译：太好了：卡介苗疫苗过量管理

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摘要

A 14-year-old girl was inadvertently immunised with an excessively large dose of BCG-Connaught vaccine (1.0 ml instead of 0.1 ml). Examination of the patient a few hours later revealed a subcutaneous fluctuant tender lump at the injection site. This was surgically excised within 12 h of immunisation and she was treated with isoniazid and rifampicin for six weeks. The patient developed no complications, other than a minor surgical scar. This case highlights the importance of the correct administration and dosing of BCG vaccine and suggests a management option that may prevent the severe local and systemic complications that are frequently associated with BCG overdose.
机译：一名14岁女孩意外接种了过量的BCG-Connaught疫苗（1.0 ml代替0.1 ml）。几个小时后对病人进行检查，发现注射部位皮下有起伏的嫩块。在免疫后12小时内手术切除，并用异烟肼和利福平治疗了6周。除轻微的手术疤痕外，患者未发生任何并发症。该病例突出了正确施用和接种BCG疫苗的重要性，并提出了一种可预防可能与BCG过量相关的严重局部和全身并发症的管理选择。

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