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首页> 外文期刊>Vaccine >Effects of astragalus polysaccharides on immunologic function of erythrocyte in chickens infected with infectious bursa disease virus
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Effects of astragalus polysaccharides on immunologic function of erythrocyte in chickens infected with infectious bursa disease virus

机译：黄芪多糖对鸡传染性法氏囊病病毒感染鸡红细胞免疫功能的影响

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摘要

160 Haline white chickens at 25 days old, negative for antibody to infectious bursa disease virus (IBDV), were randomly allocated into four groups. Chickens in groups 2-4 were infected with 0.3 ml IBDV at 26 days old. Chickens in groups 3 and 4 were injected respectively with 5 and 10 mg astragalus polysaccharide (APS) for 6 consecutive days from the first day of infection. At 21, 29, 32, 35 and 38 days old, the blood samples were taken from heart, and erythrocyte-C-3b receptor rosette rate (E-C3bRR), erythrocyte-C-3b immune complex rosette rate (E-ICRR), erythrocyte rosette forming enhancing rate (ERER) and erythrocyte rosette forming inhibitory rate (ERIR) were measured. The results showed that E-C3bRR and ERER significantly declined in chicken infected with IBDV (p<0.01); E-C3bRR, E-ICRR and ERER in groups 3 and 4 treated with APS were higher than that in groups 1 and 2 (p<0.01). the ERIR in groups 3 and 4 is similar to that in group 1. The results suggest that the immunological function of chicken erythrocytes declines after infected with IBDV and APS obviously enhances the immunological function of chicken erythrocytes
机译：将25天大，对传染性法氏囊病病毒（IBDV）抗体呈阴性的160只盐渍小鸡随机分为四组。第2-4组的鸡在26日龄时被0.3ml IBDV感染。从感染的第一天起，连续6天分别向第3组和第4组的鸡注射5和10 mg黄芪多糖（APS）。在21、29、32、35和38天大时，从心脏中采集血液样本，并获得红细胞C-3b受体玫瑰花结率（E-C3bRR），红细胞C-3b免疫复合物玫瑰花结率（E-ICRR）分别测定红细胞玫瑰花结形成抑制率（ERER）和红细胞玫瑰花结抑制率（ERIR）。结果表明，感染IBDV的鸡的E-C3bRR和ERER显着下降（p <0.01）。 APS治疗的第3和第4组的E-C3bRR，E-ICRR和ERER高于第1和第2组（p <0.01）。第3组和第4组的ERIR与第1组相似。结果表明，IBDV和APS感染后，鸡红细胞的免疫功能下降，明显增强了鸡红细胞的免疫功能。

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