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A review of emergency foot-and-mouth disease (FMD) vaccines

机译:口蹄疫紧急疫苗回顾

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The primary objectives of this paper are to describe emergency foot-and-mouth disease (FMD) vaccines and review literature on emergency vaccine efficacy to protect animals against (1) clinical signs and (2) infection (local virus replication). The reviewed experiments suggest that in cattle, sheep and pigs, the vaccine could be effective in preventing disease within 4-5 days post-vaccination. These studies also suggest that the risk of spreading infection decreases as the interval between vaccine and challenge increases and that vaccination could reduce the amount of virus excreted compared to non-vaccinated animals. We suggest areas of future research to improve our knowledge of emergency vaccines.
机译:本文的主要目的是描述紧急口蹄疫(FMD)疫苗,并综述有关紧急疫苗功效的文献,以保护动物免受(1)临床体征和(2)感染(局部病毒复制)的侵害。审查过的实验表明,在牛,羊和猪中,疫苗可在接种后4-5天内有效预防疾病。这些研究还表明,随着疫苗和攻击时间间隔的增加,传播感染的风险会降低,与未接种疫苗的动物相比,接种疫苗可能会减少排出的病毒数量。我们建议未来的研究领域,以提高我们对应急疫苗的了解。

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