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首页> 外文期刊>Vaccine >Incidence of dog bite and anti-rabies vaccine utilization in the, University of Benin Teaching Hospital, Benin City, Nigeria: A 12-year assessment
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Incidence of dog bite and anti-rabies vaccine utilization in the, University of Benin Teaching Hospital, Benin City, Nigeria: A 12-year assessment

机译：尼日利亚贝宁市贝宁大学教学医院的狗咬伤和抗狂犬病疫苗使用率：12年评估

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Aim: To assess the incidence of dog bite and utilization of anti-rabies vaccine between January 1997 and December 2008.Methods: Reported cases of dog bite from archives were collected and analyzed in the Accident and Emergency Centre of the University of Benin Teaching Hospital, Benin City, Nigeria.Result: A total of 143 cases were reported and none was previously immunized. They were between 14 and 64 years with male and female ratio 7.2:1. Among them, 53% cases were reported within 24 h, 36% cases were reported after 30 days and 11% cases reported after two months of affliction. Limbs were most afflicted. Forty-two [29.37%] patients had multiple sites of bite. Minor bleeding was in [71.33%] victims. Five hundred and eighty-seven doses of Rabipur (R) brand of anti-rabies vaccines of which 65.42% were administered intradermally and 34.58% were administered intramuscularly. Only 71% of the victims were treated with Imogam Rabies (R) brand of Rabies Immunoglobulin G. Sixty-three dog owners claimed that their dogs were vaccinated. Of the total victims, 137[95.80%] completed their routine 5 days anti-rabies regimen. Forty-seven (32.87%) were hospitalized; maximum duration was [167 +/- 0.71 h]. Ciprofloxacin and paracetamol were most frequently used antibacterial and anti-inflammatory agents, respectively. All had anti-tetanus sera.One had traditional medication prior to report presented with clinical sign of hydrophobia. He died despite therapy.Conclusion: The incidence of dog bite although rare, there is need for adequate procurement and stocking of anti-rabies vaccine to meet the need of the afflicted in this region
机译：目的：评估1997年1月至2008年12月期间狗咬伤的发生率和使用抗狂犬病疫苗的方法。方法：从贝宁大学教学医院急诊中心收集并分析报告的狗咬伤病例。结果：总共报告了143例病例，以前没有进行过免疫。他们在14至64岁之间，男女比例为7.2：1。其中，24小时内报告53％，30天后报告36％，患病两个月后报告11％。肢体受害最深。 42名[29.37％]患者有多个咬伤部位。 [71.33％]受害人轻微出血。 587剂Rabipur（R）品牌的抗狂犬病疫苗，其中65.42％皮内注射，34.58％肌内注射。仅71％的受害者接受了Imogam Rabies（R）品牌的狂犬病免疫球蛋白G的治疗。63个狗的主人声称他们的狗已经接种了疫苗。在全部受害者中，有137 [95.80％]人完成了他们常规的5天狂犬病防制方案。住院了四十七（32.87％）;最大持续时间为[167 +/- 0.71 h]。环丙沙星和扑热息痛分别是最常用的抗菌和消炎药。所有患者均具有抗破伤风血清。在报告出现疏水症的临床症状之前，其中一名患者曾接受过传统药物治疗。尽管经过治疗他还是死了。结论：狗咬伤的发生率虽然很少见，但仍需要适当采购和储备抗狂犬病疫苗来满足该地区患病者的需求。

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