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Efficacy of foot-and-mouth disease vaccine in pigs with single dose immunization

机译：单剂免疫猪口蹄疫疫苗的功效

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摘要

Two experiments were conducted to demonstrate the efficacy of a commercial foot-and-mouth disease (FMD) vaccine in pigs born to well-vaccinated sows at various ages with a single injection under field conditions. The first experiment showed that single dose vaccination of pigs could be conducted at an age younger than 10 weeks. Second experiment demonstrated that pigs vaccinated once at the age of 8 weeks had mean serum neutralization (SN) titer of 1.89 +/- 0.95 log(10)SN(50) with full protection by challenge test at the age of 24 weeks. Results indicate that the most appropriate age for single dose FMD vaccination in pigs born to well-vaccinated sows would be at 8 weeks.
机译：进行了两个实验，以证明商业口蹄疫疫苗在田间条件下单次注射对不同年龄母猪进行了良好免疫接种后所产生的猪的功效。第一个实验表明，可以在小于10周龄的年龄对猪进行单剂量疫苗接种。第二项实验表明，在8周龄时接种一次的猪在24周龄时平均血清中和（SN）滴度为1.89 +/- 0.95 log（10）SN（50），并且通过攻击试验得到全面保护。结果表明，在母猪接种良好疫苗的猪中，单剂量FMD疫苗接种的最合适年龄为8周。

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