...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Vaccine >Sero-epidemiology of measles and mumps in Korea: impact of the catch-up campaign on measles immunity.
【24h】

Sero-epidemiology of measles and mumps in Korea: impact of the catch-up campaign on measles immunity.

机译：韩国的麻疹和腮腺炎血清流行病学：追赶运动对麻疹免疫力的影响。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A catch-up campaign targeting children aged 8-16 years using measles-rubella (MR) vaccine was conducted during 2001 in Korea. To evaluate the impact of the campaign and assess mumps immunity, human IgG antibodies were detected using ELISA for measles (5826 samples) and mumps (5890 samples) in a national sample of opportunistically collected sera from a population aged 0-34 years. The measles immunity increased by 5-10% following the catch-up campaign in the targeted age group. Infants lost maternal antibodies rapidly and about 90% of infants were susceptible to measles and mumps at 6-8 months of life. The sero-prevalence of mumps antibody increased slowly with age and stabilized at a lower level when compared with that of measles. Despite an immediate reduction in susceptibility among the targeted age group of the catch-up campaign, continuous efforts to increase immunization coverage are needed to interrupt indigenous measles transmission. Furthermore, our results suggest continuous mumps outbreaks could occur because of the accumulation of susceptible individuals.
机译：2001年在韩国开展了针对使用麻疹-风疹（MR）疫苗的8-16岁儿童的追赶运动。为了评估这项运动的影响并评估腮腺炎的免疫力，使用ELISA方法检测了0-34岁年龄人群的全国血清中的麻疹（5826个样本）和腮腺炎（5890个样本）中的人IgG抗体。在目标年龄段的追赶运动后，麻疹免疫力提高了5-10％。婴儿迅速失去母体抗体，大约90％的婴儿在6-8个月的生命中易患麻疹和腮腺炎。与腮腺炎相比，腮腺炎抗体的血清感染率随年龄增长缓慢，并稳定在较低水平。尽管追赶运动的目标年龄组的易感性立即降低，但仍需要继续努力以扩大免疫覆盖率，以中断土著麻疹的传播。此外，我们的结果表明，由于易感人群的聚集，可能会出现连续性腮腺炎暴发。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号