Antibody induction after combined application of an adjuvanted recombinant FeLV vaccine and a multivalent modified live virus vaccine with a chlamydial component

Brunner C; Kanellos T; Meli ML; Sutton DJ; Gisler R; Gomes-Keller MA; Hofmann-Lehmann R; Lutz H

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Antibody induction after combined application of an adjuvanted recombinant FeLV vaccine and a multivalent modified live virus vaccine with a chlamydial component

机译：联合应用佐剂重组FeLV疫苗和带有衣原体成分的多价修饰活病毒疫苗后的抗体诱导

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The compatibility, safety and interaction on antibody induction of a combined vaccine application were assessed. Specific pathogen-free cats were vaccinated with either a modified live virus vaccine containing feline calici- (FCV), herpes- (FHV-1), parvovirus (FPV) and Chlamydophila felis (C. felis), an adjuvanted recombinant feline leukaemia virus (FeLV) vaccine or both vaccines in one syringe. After combined application, FeLV ELISA antibody titres were unaltered, However antibody production based on indirect immunofluorescence assay was remarkably enhanced for FCV and was at selected time points also enhanced for FHV-1 and C. felis but diminished for FPV. The use of these vaccines in combination was safe and will simplify vaccination schedules in veterinary practice.

机译：评估了联合疫苗应用中抗体诱导的相容性，安全性和相互作用。特定的无病原体猫用改良的活病毒疫苗接种，该疫苗包含猫杯状病毒（FCV），疱疹-病毒（FHV-1），细小病毒（FPV）和猫衣原体（C. felis），一种佐剂重组猫白血病病毒（ FeLV）疫苗或两种疫苗都装在一个注射器中。联合应用后，FeLV ELISA抗体滴度保持不变，但是基于间接免疫荧光测定的抗体产量对于FCV显着提高，并且在选定的时间点FHV-1和屎肠梭菌也有所提高，但FPV却有所减少。组合使用这些疫苗是安全的，并且可以简化兽医实践中的疫苗接种时间表。

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《Vaccine》 |2006年第11期|共9页
作者
Brunner C; Kanellos T; Meli ML; Sutton DJ; Gisler R; Gomes-Keller MA; Hofmann-Lehmann R; Lutz H;
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中图分类卫生标准、卫生检查、医药管理;
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1. Antibody induction after combined application of an adjuvanted recombinant FeLV vaccine and a multivalent modified live virus vaccine with a chlamydial component [J] . Brunner C, Kanellos T, Meli ML, Vaccine . 2006,第11期

机译：联合应用佐剂重组FeLV疫苗和带有衣原体成分的多价修饰活病毒疫苗后的抗体诱导
2. Efficacy of a Non-adjuvanted, Modified-live Virus Vaccine in Calves with Maternal Antibodies against a Virulent Bovine Viral Diarrhea Virus Type 2a Challenge Seven Months following Vaccination [J] . Stevens Elliot T., Brown Michael S., Burdett William W., The Bovine Practitioner . 2011,第1期

机译：疫苗接种七个月后，带有母体抗体的犊牛非佐剂，改良活病毒疫苗对母猪产生2a型强毒腹泻病毒的功效
3. Protection against bovine respiratory syncytial virus in calves vaccinated with adjuvanted modified live vaccine administered in the face of maternal antibody [J] . Kolb Elizabeth A., Buterbaugh Robin E., Rinehart Carol L., Vaccine . 2020,第2期

机译：在母体抗体面部施用的佐剂修饰的活疫苗接种牛犊中的牛呼吸道合胞病毒的保护
4. Onset of immunity in 8-week-old piglets without antibodies against Aujeszky's disease, after vaccination with a live, recombinant oil-in-water adjuvanted Aujeszky's disease vaccine (Suvaxyn 783+o/w) [C] . A. Kersten, T. Dazelle, A. van de Galien, Congress of the International Pig Veterinary Society . 1999

机译：在8周龄仔猪的免疫发作，没有针对Aujeszky的疾病的抗体，在用活疫苗接种后，重组含油辅助Aujeszky的疾病疫苗（Suvaxyn 783 + O / W）
5. The immune response in horses to vaccination against equine influenza virus. A comparison of recombinant DNA, inactivated-virus, and modified-live virus vaccines. [D] . Sweat, James Mark. 2001

机译：马对马流感病毒疫苗的免疫反应。重组DNA，灭活病毒和改良活病毒疫苗的比较。
6. Antibody induction after combined application of an adjuvanted recombinant FeLV vaccine and a multivalent modified live virus vaccine with a chlamydial component [O] . Chantal Brunner, Theo Kanellos, Marina L. Meli, -1

机译：联合应用佐剂重组FeLV疫苗和带有衣原体成分的多价修饰活病毒疫苗后的抗体诱导
7. Antibody induction after combined application of an adjuvanted recombinant FeLV vaccine and a multivalent modified live virus vaccine with a chlamydial component [O] . Chantal Brunner, Theo Kanellos, Marina L. Meli, 2006

机译：组合辅助重组FELV疫苗和用衣原体组分的多元改性活病毒疫苗施用抗体诱导

Antibody induction after combined application of an adjuvanted recombinant FeLV vaccine and a multivalent modified live virus vaccine with a chlamydial component

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