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首页> 外文期刊>Vox Sanguinis: International Journal of Blood Transfusion and Immunohaematology >Bacterial skin flora and contamination of blood components: Do we defer blood donors wisely?
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Bacterial skin flora and contamination of blood components: Do we defer blood donors wisely?

机译：细菌皮肤菌群和血液成分污染：我们是否明智地推迟了献血者？

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Background and objectives Bacterial infection through contaminated blood is currently the greatest infection risk in relation to a transfusion. Deferral of prospective blood donors with a skin disorder is a common practise, because bacteria usually originate from the donor's skin. The effectiveness of current deferral guidelines to prevent the bacterial contamination of blood has not been assessed. Materials and methods We recruited 55 blood donors with a skin disorder that prevented donation, and matched three controls for each case. The donors filled out a questionnaire and one bacterial culture sample was taken from venepuncture forearm skin. Results The median total number of colony forming skin bacteria was significantly higher in the cases (224 CFUs per sample) than controls (105CFU per sample). Staphylococcus aureus was significantly more often present on the skin in cases (49%) as compared to controls (7%). Regarding other bacterial genera, no difference between cases and controls was found. Conclusions This study shows that our current guidelines for deferral of blood donors with skin disorders effectively identifies individuals with a high number of bacteria on their skin, as well as S. aureus carriers. However, deferral due to skin disorders had only a minor impact on blood product contamination when compared to other actions.
机译：背景和目的目前，通过污染的血液进行细菌感染是与输血有关的最大感染风险。推迟患有皮肤病的潜在献血者是一种常见的做法，因为细菌通常起源于献血者的皮肤。当前的延期指南对预防血液中细菌污染的有效性尚未评估。材料和方法我们招募了55名皮肤疾病的献血者，这些疾病阻止了捐赠，并针对每种情况匹配了三个对照。捐献者填写了一份问卷，并从前庭前庭穿刺皮肤中获取了一个细菌培养样品。结果在这种情况下（每个样品224 CFU），中位数形成菌落总数明显高于对照组（每个样品105 CFU）。与对照组（7％）相比，病例中（49％）的皮肤中金黄色葡萄球菌的出现率更高。关于其他细菌属，病例与对照之间没有发现差异。结论这项研究表明，我们目前的延缓皮肤疾病献血者的指南有效地确定了皮肤上带有大量细菌以及金黄色葡萄球菌携带者的个体。但是，与其他措施相比，由于皮肤疾病引起的延期对血液制品的污染影响很小。

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