...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Dalton transactions: An international journal of inorganic chemistry >Water-stable ammonium-terminated carbosilane dendrimers as efficient antibacterial agents
【24h】

Water-stable ammonium-terminated carbosilane dendrimers as efficient antibacterial agents

机译：水稳定的铵基碳硅烷树枝状大分子作为有效的抗菌剂

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A new family of amine- and ammonium-terminated carbosilane dendrimers of the type G(n)-[Si(CH2)(3)N(Et)CH2CH2NMe2](x) and G(n)-{[Si(CH2)(3)N+R(Et)CH2CH2N+RMe2](x)(X-)(y)} (where n = 1, 2 and 3; R= H, X = Cl; R = Me, X = I) respectively has been synthesized by hydrosilylation of N,N-dimethyl-N'-allyl-N'-ethyl-ethylenediamine, [(CH2=CH-CH2)(Et)N(CH2)(2)NMe2] with the corresponding hydride-terminated dendrimers and subsequent quaternization with HCl or MeI. Quaternized dendrimers are soluble and stable in water or other protic solvents for long time periods. The antibacterial properties of the quaternary ammonium functionalized dendrimers have been evaluated showing that they act as potent biocides in which the multivalency along with the biopermeability of the carbosilane dendritic skeleton play an important role in the antibactericidal activity of these compounds.
机译：G（n）-[Si（CH2）（3）N（Et）CH2CH2NMe2]（x）和G（n）-{[Si（CH2）（ 3）N + R（Et）CH2CH2N + RMe2]（x）（X-）（y）}（其中n = 1、2和3; R = H，X = Cl; R = Me，X = I）已通过N，N-二甲基-N'-烯丙基-N'-乙基-乙二胺[[CH2 = CH-CH2）（Et）N（CH2）（2）NMe2]与相应的氢化物封端的氢化硅烷化反应合成树枝状聚合物，随后用HCl或MeI季铵化。季铵化的树枝状大分子在水或其他质子溶剂中可溶解且稳定很长时间。已评估了季铵官能化树状聚合物的抗菌性能，表明它们可作为有效的杀生物剂，其中碳硅烷树状骨架的多价以及生物渗透性在这些化合物的抗菌活性中起重要作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号