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首页> 外文期刊>Dalton transactions: An international journal of inorganic chemistry >Molecular details of multielectron transfer: the case of multiheme cytochromes from metal respiring organisms
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Molecular details of multielectron transfer: the case of multiheme cytochromes from metal respiring organisms

机译:多电子转移的分子细节:来自金属呼吸生物的多血红素细胞色素

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摘要

Shewanella are facultative anaerobic bacteria of remarkable respiratory versatility that includes the dissimilatory reduction of metal ores. They contain a large number of multiheme c-type cytochromes that play a significant role in various anaerobic respiratory processes. Of all the cytochromes found in Shewanella, only the two most abundant periplasmic cytochromes, the small tetraheme cytochrome (STC) and flavocytochrome c(3) (Fcc(3)) have been structurally characterized. For these two proteins the molecular bases for their redox properties were determined using spectroscopic methods based on paramagnetic NMR, that allow the contribution of specific hemes to be discriminated. In this perspective these results are reviewed in the context of the continuing effort to understand the molecular mechanisms of electron transfer in the respiratory chains of these organisms.
机译:希瓦氏菌是兼具呼吸功能的兼性厌氧细菌,包括金属矿石的异化还原。它们包含大量在各种厌氧呼吸过程中发挥重要作用的多血红素c型细胞色素。在希瓦氏菌中发现的所有细胞色素中,只有两种最丰富的周质细胞色素,即小四血红素细胞色素(STC)和黄素细胞色素c(3)(Fcc(3))具有结构特征。对于这两种蛋白质,使用基于顺磁性NMR的光谱方法确定了其氧化还原特性的分子碱基,这可以区分特定的血红素。从这个角度来看,在不断努力了解这些生物的呼吸链中电子转移的分子机制的背景下,对这些结果进行了综述。

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