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New polyoxometalate/starch nanomaterial: synthesis,characterization and antitumoral activity

机译:新型多金属氧酸盐/淀粉纳米材料:合成,表征和抗肿瘤活性

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摘要

Using a reversed-phase microemulsion polymerization method,polyoxometalate (POM) CoW_(11)TiO_(40) loaded starch nanoparticles have been prepared and structurally characterized by elemental analyses,IR spectra,UV-vis and ESR spectroscopy.The particle size of CoW_(11)TiO_(40)/starch was estimated by transmission electron microscopy (TEM) and the size ranges by a 1000HSA MALVIRN Zetasizer instrument.The results show that the POMs retained the parent structure after encapsulated by starch microspheres,which are able to enhance the stability and antitumoral activity of POMs and also decrease the toxicity of the POM.
机译:采用反相微乳液聚合法制备了载有多金属氧酸盐(POM)的CoW_(11)TiO_(40)淀粉纳米粒子,并通过元素分析,红外光谱,紫外可见和ESR光谱对其结构进行了表征。 11)用透射电子显微镜(TEM)估算TiO_(40)/淀粉含量,并用1000HSA MALVIRN Zetasizer仪器测定其粒径范围,结果表明,POMs经淀粉微球包封后保留了母体结构,能够增强POM的稳定性和抗肿瘤活性,还降低了POM的毒性。

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