Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

Allen OR; Knox RJ; McGowan PC

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Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

机译：功能化的环戊二烯基锆化合物作为潜在的抗癌药

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New neutral and ionic functionalised zirconocene dichloride compounds have been isolated and characterised. The ionic zirconocene exhibits excellent cytotoxicity against a range of human tumour cell lines, which represents the first active anticancer zirconocene dichloride compound.

机译：分离并鉴定了新的中性和离子官能化二茂锆二氯化物化合物。离子锆茂对多种人类肿瘤细胞系表现出优异的细胞毒性，这是第一种活性的抗癌性锆二氯化物化合物。

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《Dalton transactions: An international journal of inorganic chemistry》 |2008年第39期|共3页
作者
Allen OR; Knox RJ; McGowan PC;
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正文语种 eng
中图分类无机化学;
关键词
COLONY-FORMING-UNITS; SUBSTITUTED TITANOCENES; ORGANOMETALLIC COMPOUNDS; METALLOCENE DICHLORIDES; TITANIUM DICHLORIDE; ANTITUMOR-ACTIVITY; ASCITES TUMOR; CYTOTOXICITY; DERIVATIVES; INHIBITION;

机译：菌落形成单位;取代的钛烯酮;有机金属化合物;茂金属二氯化钛;二氯化钛;抗原活性;骨肿瘤;细胞毒性;衍生物;抑制作用;

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专利

1. Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs [J] . Allen OR, Knox RJ, McGowan PC Dalton transactions: An international journal of inorganic chemistry . 2008,第39期

机译：功能化的环戊二烯基锆化合物作为潜在的抗癌药
2. Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential [J] . Leonor C?rte-Real, Ricardo G. Teixeira, Patrícia Gírio, Inorganic Chemistry: A Research Journal that Includes Bioinorganic, Catalytic, Organometallic, Solid-State, and Synthetic Chemistry and Reaction Dynamics . 2018,第8期

机译：甲基 - 环戊二烯基钌化合物与2,2'-硼啶衍生物显示出强烈的抗癌活性和多药耐药潜力
3. Novel enantiopure cyclopentadienyl Ti(IV) oximato compounds as potential anticancer agents [J] . de la Cueva-Alique Isabel, Munoz-Moreno Laura, Benabdelouahab Yosra, Journal of Inorganic Biochemistry: An Interdisciplinary Journal . 2016,第Null期

机译：新型对映体纯的环戊二烯基Ti（IV）肟酸酯化合物作为潜在的抗癌药
4. Nano_doped Rare Earth Compounds for Application of Anticancer Drugs [C] . Guilin Lu, ShaoHong Wang, HaiYuan Xie, International conference on opto-electronics engineering and information science . 2011

机译：纳米掺杂稀土化合物在抗癌药物中的应用
5. High-resolution NMR spectroscopic analysis of anticancer drugs, DNA and their interactions: 1. Platinum anticancer compounds - DNA interactions. 2. Anthracycline drugs - DNA interactions and modified DNA. [D] . Yang, Danzhou. 1996

机译：抗癌药物，DNA及其相互作用的高分辨率NMR光谱分析：1.铂类抗癌化合物-DNA相互作用。 2.蒽环类药物-DNA相互作用和修饰的DNA。
6. Novel enantiopure cyclopentadienyl Ti(IV) oximato compounds as potential anticancer agents [O] . Isabel de la Cueva-Alique, Laura Muñoz-Moreno, Yosra Benabdelouahab, -1

机译：新型对映体纯的环戊二烯基Ti（IV）肟酸酯化合物作为潜在的抗癌药
7. Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential [O] . Leonor Côrte-Real, Ricardo G. Teixeira, Patrícia Gírio, 2018

机译：甲基 - 环戊二烯基钌化合物与2,2'-硼啶衍生物显示出强烈的抗癌活性和多药耐药潜力

Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

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