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首页> 外文期刊>Dermatologic surgery >Management of squamous cell carcinoma in a patient with recessive-type epidermolysis bullosa dystrophica.
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Management of squamous cell carcinoma in a patient with recessive-type epidermolysis bullosa dystrophica.

机译：隐性表皮松解性大疱性营养不良患者的鳞状细胞癌的处理。

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摘要

Background. Surgical treatment of a recessive dystrophic epidermolysis bullosa patient is very difficult for both the surgeon and the anesthetist because of the fragility of the skin and abnormal nature of the tumor bed. Objective. We report a case of 54-year-old Japanese recessive dystrophic epidermolysis bullosa patient with squamous cell carcinoma (SCC) of the lateral malleolus. Methods. A tumor measuring 5.0 x 5.5 cm was surgically excised. The defect was then reconstructed by full-thickness skin grafting. To avoid airway complications, general anesthesia was administered using a face mask. Because the regional lymph nodes were swollen before surgery, the patient underwent sentinel lymph node biopsy. Results. The patient remains well with no sign of recurrence or metastasis 7 months after surgery. Conclusion. To preserve activities of daily living, surgery should be performed for squamous cell carcinomas arising in recessive dystrophic epidermolysis bullosa patients. MIZUKI YAMADA, MD, NAOHITO HATTA, MD, PHD, KANA SOGO, MD, KAZUHIRO KOMURA, MD, YASUHITO HAMAGUCHI, MD, PHD, AND KAZUHIKO TAKEHARA, MD, PHD HAVE INDICATED NO SIGNIFICANT INTEREST WITH COMMERCIAL SUPPORTERS.
机译：背景。对于外科医生和麻醉师来说，对于隐性营养不良性大疱性表皮松解症的外科手术治疗是非常困难的，因为皮肤脆弱且肿瘤床的性质异常。目的。我们报告54例日本隐性营养不良性表皮松解性大疱性伴外踝鳞状细胞癌（SCC）患者。方法。手术切除5.0 x 5.5 cm的肿瘤。然后通过全厚度皮肤移植重建缺损。为避免气道并发症，使用面罩进行全身麻醉。由于术前局部淋巴结肿大，患者接受了前哨淋巴结活检。结果。术后7个月，患者情况良好，无复发或转移迹象。结论。为了保持日常生活活动，应对隐性营养不良性大疱性表皮松解症患者中发生的鳞状细胞癌进行手术。马里兰州山田铃木，马里兰州博士，OH田直人，马里兰州博士，小浦一郎医学博士，PHD博士山口靖人和马里兰州立博士等人对商业支持者没有明显的兴趣。

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