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首页> 外文期刊>Dermatologic surgery >Digital dermoscopic monitoring of atypical nevi in patients at risk for melanoma.
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Digital dermoscopic monitoring of atypical nevi in patients at risk for melanoma.

机译：对有黑素瘤风险的患者进行非典型痣的数字皮肤镜监测。

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摘要

BACKGROUND: Atypical nevi are a common risk factor for melanoma. OBJECTIVES: The objective was to determine the utility of monitoring dermoscopic photographs of atypical nevi in a high-risk population. METHODS: Over a 4.5-year period, digital dermoscopic photographs were taken of clinically atypical nevi at initial and follow-up visits, such that side-by-side comparisons could be made. RESULTS: A total of 5,945 lesions were monitored in 297 patients over 3 to 52 months (median, 22 months), and 324 lesions were biopsied. Photographic (dermoscopic) changes were noted in 96 of 5,945 (1.6%) lesions, which included 64 dysplastic nevi (67%), 25 common nevi (26%), and 1 melanoma (1.0%). Of 6 melanomas biopsied during the follow-up period, only 1 was detected by dermoscopic photographic change at follow-up. CONCLUSIONS: Most clinically atypical melanocytic nevi are stable over time, and lesions exhibiting dermoscopic changes are most likely to be dysplastic nevi. Although dermoscopy is a useful tool for clinical examination, the sensitivity of dermoscopic monitoring is limited by melanomas that may arise in normal skin or in clinically benign nevi that were not initially photographed.
机译：背景：非典型痣是黑色素瘤的常见危险因素。目的：目的是确定监测高危人群中非典型痣的皮肤镜照片的实用性。方法：在4。5年的时间里，在初次和随访时，对临床上非典型痣进行了数码皮肤镜照相，从而可以进行并排比较。结果：在3到52个月（中位数为22个月）中对297例患者进行了共5945处病变的监测，并对324处病变进行了活检。在5,945个病变中有96个（皮肤）镜检（皮下）改变，包括64个增生性痣（67％），25个普通痣（26％）和1个黑色素瘤（1.0％）。在随访期间进行活检的6例黑色素瘤中，在随访时仅1例通过皮肤镜照相术检出。结论：大多数临床上非典型的黑素细胞痣随着时间的推移是稳定的，表现出皮肤镜改变的病变最可能是增生性痣。尽管皮肤镜检查是用于临床检查的有用工具，但皮肤镜监测的敏感性受到正常皮肤或临床上未曾照相的良性痣中可能出现的黑色素瘤的限制。

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