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首页> 外文期刊>Dermatologic surgery >Ultraviolet-fluorescent tattoo location of cutaneous biopsy site
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Ultraviolet-fluorescent tattoo location of cutaneous biopsy site

机译：皮肤活检部位的紫外线荧光纹身位置

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Background Cutaneous biopsies often heal with little or no scarring. Prior studies have shown an alarming percentage of patients who incorrectly identify biopsy sites at the time of surgery. Objective To investigate the safety and utility of an ultraviolet (UV)-fluorescent tattoo for biopsy site identification. Materials and Methods A preclinical proof of concept was established with skin culture. An UV-fluorescent tattoo was applied to discarded neonatal foreskin in culture medium. The stability of the tattooed skin was examined clinically and histologically. One patient with a recurrent basal cell carcinoma in a difficult-to-identify location underwent tattoo application at the time of biopsy to demarcate the site. The patient was monitored for tattoo reaction and referred for surgical excision. Results The cultured tissue exhibited stable UV fluorescence with daily washing. Tissue histology demonstrated tattoo particles lining the skin edge under fluorescent microscopy. The patient was reluctant to undergo another surgical procedure and instead returned to our clinic at 3 months and 17 months after the biopsy for management of other tumors. The patient had no symptoms of allergic reaction to the tattoo dye. The fluorescent tattoo remains invisible under visible light and visible only under Wood's light. Conclusion The present study documents the utility of an UV-fluorescent tattoo to locate a biopsy site.
机译：背景技术皮肤活检通常愈合时几乎没有或没有疤痕。先前的研究表明，在手术时错误地识别活检部位的患者比例惊人。目的探讨紫外荧光纹身在活检部位识别中的安全性和实用性。材料和方法通过皮肤培养建立了临床前概念证明。将紫外线荧光纹身应用于培养基中废弃的新生儿包皮。临床和组织学检查了纹身皮肤的稳定性。一名在难以确定位置的复发性基底细胞癌患者在活检时划定了纹身位置。监测患者的纹身反应并转介手术切除。结果培养的组织在每天洗涤后表现出稳定的紫外荧光。组织组织学显示在荧光显微镜下衬在皮肤边缘的纹身颗粒。该患者不愿进行其他手术，而是在活检后3个月和17个月返回我们的诊所以处理其他肿瘤。患者没有对纹身染料的过敏反应症状。荧光纹身在可见光下保持不可见，仅在伍德的光下可见。结论本研究证明了使用紫外线荧光纹身来定位活检部位的实用性。

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