Basal cell carcinoma (BCC) is a common neoplasm of the skin with well-known variability in morphology. The most common nodular type consists of islands and nests of uniform palisading basaloid cells often exhibiting stromal retraction artifact, mucin within the stroma, and an associated mononuclear infiltrate. Other common subtypes of BCC include superficial, micronodular, infiltrating, morpheaform (sclerosing), and basosquamous (metatypical). Less common variants include adenoid and adamantinoid (amelob-lastoma-like). Attempts have been made to associate histologic variants with differences in biologic behavior. For example, morpheaform, infiltrating, and basosquamous BCCs have been associated with aggressive behavior, including perineural invasion
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