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首页> 外文期刊>Dermatologic surgery >Treatment of punched-out atrophic and rolling acne scars in skin phototypes III, IV, and V with variable square pulse erbium:yttrium-aluminum-garnet laser resurfacing.
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Treatment of punched-out atrophic and rolling acne scars in skin phototypes III, IV, and V with variable square pulse erbium:yttrium-aluminum-garnet laser resurfacing.

机译：用可变方脉冲：钇铝石榴石激光换肤治疗III型，IV型和V型皮肤光斑的萎缩性和滚动性痤疮疤痕。

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BACKGROUND: Treatment of acne scars remains a challenge, especially in dark-skinned individuals. Treatment parameters may be optimized by selecting appropriate pulse width and laser energy that enhance tissue thermal response with limited morbidity. OBJECTIVE: To determine the efficacy and side effects of variable square pulse (VSP) erbium:yttrium-aluminum-garnet (Er:YAG) laser resurfacing for treatment of punched-out atrophic and rolling acne scars. METHODS Twenty-four subjects with acne scars were treated monthly for 2 months with four passes of VSP Er:YAG laser resurfacing using a 7-mm spot size and a fluence of 0.4 J/cm(2). Subjects were divided into two groups and treated with two different pulse widths: 300 micros (short pulse, SP) and 1,500 micros (extra-long pulse, XLP). Objective and subjective assessments were obtained at baseline and 1, 2, and 4 months after treatment. RESULTS: In the SP group, skin smoothness improved significantly (p<.01); in the XLP group, skin smoothness (p<.05) and scar volume (p<.05) improved significantly from baseline. Adverse effects consisted of transient postinflammatory hyperpigmentation (18%) and acneiform eruption (9%). CONCLUSIONS: Low-fluence VSP Er:YAG laser resurfacing is a promising treatment option for acne scars, with minimal risk of side effects. Laser pulse width and energy determine the efficacy and the risk of side effects. The authors have indicated no significant interests with commercial supporters.
机译：背景：痤疮疤痕的治疗仍然是一个挑战，特别是在皮肤黝黑的人中。可以通过选择适当的脉冲宽度和激光能量来优化治疗参数，这些脉冲宽度和激光能量可以提高发病率有限的组织热响应。目的：确定可变方脉冲（VSP）:：钇铝石榴石（Er：YAG）激光换肤治疗穿孔性萎缩性和滚动性痤疮疤痕的疗效和副作用。方法每月用7毫米光斑大小和0.4 J / cm（2）的通量，对VSP Er：YAG激光换肤四次，对24名痤疮疤痕患者进行为期2个月的治疗。将受试者分为两组，并用两种不同的脉冲宽度进行治疗：300微米（短脉冲，SP）和1,500微米（超长脉冲，XLP）。在基线，治疗后1、2和4个月获得客观和主观评估。结果：SP组的皮肤光滑度显着改善（p <.01）。在XLP组中，皮肤光滑度（p <.05）和疤痕量（p <.05）与基线相比有显着改善。不良反应包括短暂的炎症后色素沉着（18％）和痤疮样喷发（9％）。结论：低通量VSP Er：YAG激光换肤是治疗痤疮疤痕的有前途的治疗选择，其副作用风险最小。激光脉冲宽度和能量决定疗效和副作用风险。作者表示对商业支持者没有太大兴趣。

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